948304-44-7Relevant articles and documents
Orally bioavailable potent soluble epoxide hydrolase inhibitors
Sung, Hee Hwang,Tsai, Hsing-Ju,Liu, Jun-Yan,Morisseau, Christophe,Hammock, Bruce D.
, p. 3825 - 3840 (2007)
A series of N,N′-disubstituted ureas having a conformationally restricted cis- or trans-1,4-cyclohexane α to the urea were prepared and tested as soluble epoxide hydrolase (sEH) inhibitors. This series of compounds showed low nanomolar to picomolar activi