94833-83-7Relevant academic research and scientific papers
SYNTHESIS AND APPLICATION OF SOME NEW S-(SUBSTITUTED)THIO- AND THIENOQUINOLINE DERIVATIVES AS ANTIMICROBIAL AGENTS
Awad, Ibrahim M. A.,Abdel-Rahman, Abdu E.,Bakhite, Etify A.
, p. 1749 - 1760 (2007/10/02)
Ethyl (4-aryl-3-cyano-5,6,7,8-tetrahydro-2-quinolinylthio) acetate (IIa, IIb) were prepared and reacted with hydrazine hydrate to give hydrazides IIIa, IIIb which underwent cyclization into thienoquinoline derivatives IVa, IVb.Reaction of IIIa, IIIb with
CYCLIZATION OF NITRILES. X. ENAMINO NITRILES OF THE 1,3-DITHIA-4-CYCLOHEXENE SERIES AND THEIR RECYCLIZATION TO DERIVATIVES OF PYRIDINE AND THIAZOLE
Sharanin, Yu. K.,Shestopalov, A. M.,Promonenkov, V. K.,Rodinovskaya, L. A.
, p. 1402 - 1415 (2007/10/02)
The recyclization of 4-amino-6-aryl-5-cyano-2-cyclopentane(cyclohexane)spiro-1,3-dithia-4-cyclohexenes, obtained from gem-dithiols and arylidenemalononitriles, leads to the formation of 4-aryl-5,6-polymethylene-3-cyano-2-(1H)-pyridinethiones.The latter are used in the synthesis of various 3-aminothienopyridines, 4-aryl-3-amino-5,6,7,8-tetrahydrothienoquinolines, and other heterocyclic compounds condensed with quinoline. 1-Cyano-1-(4-aryl-2-thiazolyl)-2-arylethylenes were obtained by the reaction of the 1,3-dithia-4-cyclohexenes with phenacyl bromides.
