948844-44-8Relevant academic research and scientific papers
Lewis base assisted Bronsted base catalysis: Bidentate phosphine oxides as activators and modulators of bronsted basic lanthanum-aryloxides
Morimoto, Hiroyuki,Yoshino, Tatsuhiko,Yukawa, Takafumi,Lu, Gang,Matsunaga, Shigeki,Shibasaki, Masakatsu
, p. 9125 - 9129 (2008)
(Chemical Equation Presented) Dynamic Duo: A Lewis basic bidentate phosphine oxide was effective for activating and modulating the properties of Bronsted basic lanthanum aryl oxides. The Lewis base 1/lanthanum aryl oxide system was suitable for anti-selective Mannich-type reactions of trichloromethyl ketones (see scheme), affording unique building blocks for azetidine-2-carboxylic acids as well as β-amino acids.
Enantioselective C-C bond formation to sulfonylimines through use of the 2-pyridinesulfonyl group as a novel stereocontroller
Nakamura, Shuichi,Nakashima, Hiroki,Sugimoto, Hideki,Sano, Hideaki,Hattori, Masataka,Shibata, Norio,Toru, Takeshi
supporting information; experimental part, p. 2145 - 2152 (2009/04/08)
Enantioselective C-C bond formation to 2-pyridinesulfonylimines afforded products with good enantioselectivity. Dynamic induction of chirality on the sulfur by coordination of a chiral Lewis acid to the pyridine nitrogen and one of the prochiral sulfonyl oxygens induces enantioselectivity. Since the 2-pyridine-sulfonyl group can easily be removed after the reaction, it acts not only as an activating group but also as an efficient Stereocontroller.
