948846-22-8

Upstream product

• 106-37-6 1.4-dibromobenzene 
• 948846-77-3 tert-butyl (3aR,6aR)-1-(4-bromophenyl)hexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxylate 
• 948846-60-4 (3aR,6aR)-5-methyl-octahydro-pyrrolo[3,4-b]pyrrole-1-carboxylic acid tert-butyl ester 
• 948846-61-5 (3aR,6aR)-5-methyl-2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-b]pyrrole 
• 370880-09-4 (3aR,6aR)-octahydro-pyrrolo[3,4-b]pyrrole-1-carboxylic acid tert-butyl ester 
• 370882-39-6 tert-butyl (3AR,6AR)-hexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxylate 
• 948846-62-6 (3aR,6aR)-1-(4-bromo-phenyl)-5-methyl-octahydro-pyrrolo[3,4-b]pyrrole 
• 624-28-2 2,5-dibromopyridine 
• 948846-80-8 2-(5-bromo-pyridin-2-yl)-2H-pyridazin-3-one 
• 948846-79-5 (3aR,6aR)-5-methyl-1-(4-(4,4,5,5-tetramethyl-1,3-dioxaborolan-2-yl)-phenyl)-octahydro-pyrrolo[3,4-b]pyrrole 

Downstream Products

• 1131686-23-1 (3aR,5R,6aR)-5-methyl-1-(4-(6-(6-oxopyridazin-1(6H)-yl)pyridin-3-yl)phenyl)octahydropyrrolo[3,4-b]pyrrole 5-oxide 

Relevant academic research and scientific papers

OCTAHYDRO-PYRROLO[3,4-B]PYRROLE N-OXIDES

The invention relates to octahydro-pyrrolo[3,4-b]pyrrole N-oxides as prodrugs of CNS-active compounds, compositions comprising such compounds, methods for making the compounds, salts, and polymorphs, and methods of treating conditions and disorders using

OCTAHYDRO-PYRROLO[3,4-B]PYRROLE DERIVATIVES

Octahydro-pyrrolo[3,4-b]pyrrole derivatives are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Octahydro-pyrrolo[3,4-b]pyrrole compounds, methods for using such compounds, compositions for making th