94885-35-5

Basic information

• Product Name: 4,4-Oxazolidinedimethanol, 2-phenyl-
• CAS NO: 94885-35-5
• Molecular Formula: C11H15NO3
• Molecular Weight: 209.245
• Mol File: 94885-35-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4,4-Oxazolidinedimethanol, 2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4-Oxazolidinedimethanol, 2-phenyl-(94885-35-5)
• EPA Substance Registry System: 4,4-Oxazolidinedimethanol, 2-phenyl-(94885-35-5)

Safety Data

• Hazardous Substances Data: 94885-35-5(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 77-86-1 2-amino-2-hydroxymethyl-1,3-propanediol 

Relevant articles and documents

Stereoelectronic control of oxazolidine ring-opening: Structural and chemical evidences

Ring opening of oxazolidines derived from tris(hydroxymethyl)aminomethane, L-serine and L-threonine was investigated. It was shown that n(N)→σ*(C-O) electron delocalization (endo-anomeric effect) occurring in the five-membered ring plays a major role in the cleavage of the intracyclic C-O bond. The present work establishes that when the nitrogen lone pair is conjugated with a carbonyl group (n(N)→π(C=O) delocalization) as happens in N-acyloxazolidines, both hydrolysis and reductive ring-opening become much more difficult as a consequence of a concomitant decrease of oxygen basicity and of an increase of the intracyclic C-O bond strength.