948996-03-0

Basic information

• Product Name: 2-((6-Chloropyridazin-3-yl)Methyl)isoindoline-1,3-dione
• Synonyms: 2-((6-Chloropyridazin-3-yl)Methyl)isoindoline-1,3-dione;2-((6-Chloropyridazin-3-yl)
• CAS NO: 948996-03-0
• Molecular Formula: C13H8ClN3O2
• Molecular Weight: 273.67452
• Mol File: 948996-03-0.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 2-((6-Chloropyridazin-3-yl)Methyl)isoindoline-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((6-Chloropyridazin-3-yl)Methyl)isoindoline-1,3-dione(948996-03-0)
• EPA Substance Registry System: 2-((6-Chloropyridazin-3-yl)Methyl)isoindoline-1,3-dione(948996-03-0)

Safety Data

• Hazardous Substances Data: 948996-03-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research and Drug Development:
2-((6-Chloropyridazin-3-yl)Methyl)isoindoline-1,3-dione is utilized as a compound of interest in pharmaceutical research and drug development for its potential biological activities and therapeutic properties. It is being studied for its possible applications in the treatment of various diseases and conditions, with ongoing research aimed at uncovering its full medicinal potential.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 2-((6-Chloropyridazin-3-yl)Methyl)isoindoline-1,3-dione serves as a valuable starting point for the design and synthesis of new drugs. Its unique structure and potential biological activities make it a promising candidate for the development of novel therapeutic agents.
Used in Drug Discovery:
2-((6-Chloropyridazin-3-yl)Methyl)isoindoline-1,3-dione is employed in drug discovery processes to identify and optimize compounds with potential therapeutic effects. Its unique chemical properties and potential interactions with biological targets make it a valuable tool in the search for new treatments for various diseases and conditions.
Used in Chemical Synthesis:
In chemical synthesis, 2-((6-Chloropyridazin-3-yl)Methyl)isoindoline-1,3-dione is used as a building block or intermediate in the preparation of more complex molecules with potential applications in various industries, including pharmaceuticals, materials science, and agrochemicals.

Upstream product

• 1074-82-4 potassium phtalimide 
• 120276-59-7 3-chloro-6-pyridazinyl methyl chloride 
• 1121-79-5 3-chloro-6-methylpyridazine 
• 2439-85-2 N-bromophthalimide 

Downstream Products

• 871826-15-2 (6-chloropyridazin-3-yl)methanamine 

Relevant articles and documents

Preparation method of N-(aryl/heteroaryl) alkyl-diamide

The invention relates to a preparation method of N-(aryl/heteroaryl)alkyl- diamide, which comprises the following steps: under the protection of nitrogen, sequentially adding transition metal, phosphine or nitrogen ligand, cocatalyst, alkali, solvent, Nhalogenated cyclodiamide, alkyl aromatic ring or alkyl heteroaromatic ring compound into a reaction container, carrying out oxidative amination reaction at 80-140 DEG C, and till the reaction concludes after 6-48 hours, evaporating and drying a solvent and carrying out column chromatography separation to obtain an N (aryl/heteroaryl) alkyl diamide compound. The invention is simple in synthesis process, mild in reaction condition, high in yield and easy to industrialize.

Synthesis, herbicidal activities, and 3D-QSAR of 2-cyanoacrylates containing aromatic methylamine moieties

A series of novel 2-cyanoacrylates containing different aromatic rings were synthesized, and their structures were characterized by 1H NMR, elemental analysis, and single-crystal X-ray diffraction analysis. Their herbicidal activities against four weeds and inhibition of photosynthetic electron transport against isolated chloroplasts (the Hill reaction) were evaluated. Both in vivo and in vitro data showed that the compounds containing benzene, pyridine, and thiazole moieties gave higher activities than those containing pyrimidine, pyridazine, furan, and tetrahedronfuran moieties. To further explore the comprehensive structure-activity relationship on the basis of in vitro data, comparative molecular field analysis (CoMFA) was performed, and the results showed that a bulky and electronegative group around the para-position of the aromatic rings would have the potential for higher activity, which offered important structural insights into designing highly active compounds prior to the next synthesis.