948997-74-8Relevant academic research and scientific papers
Enantioselective Synthesis of (-)-Dysiherbaine
Do, Ha,Kang, Chang Won,Cho, Joon Hyung,Gilbertson, Scott R.
, p. 3972 - 3974 (2015)
Dysiherbaine, a natural product isolated from the Marine sponge Dysidea herbacea, has been shown to be a selective agonist of non-NMDA type glutamate receptors, kainate receptors. An enantioselective synthesis of dysiherbaine is reported. Metathesis of th
Total synthesis of dysiherbaine
Sasaki, Makoto,Akiyama, Nobuyuki,Tsubone, Koichi,Shoji, Muneo,Oikawa, Masato,Sakai, Ryuichi
, p. 5697 - 5700 (2007)
An efficient total synthesis of dysiherbaine, a potent and subtype-selective agonist for ionotropic glutamate receptors, has been achieved. An advanced key intermediate in the previous synthesis of neodysiherbaine A and its analogues was selected as the s
Rapid and efficient synthesis of dysiherbaine and analogues to explore structure-activity relationships
Sasaki, Makoto,Tsubone, Koichi,Aoki, Kunimori,Akiyama, Nobuyuki,Shoji, Muneo,Oikawa, Masato,Sakai, Ryuichi,Shimamoto, Keiko
, p. 264 - 273 (2008/09/17)
(Chemical Equation Presented) A rapid and efficient total synthesis of dysiherbaine (1), a potent and subtype-selective agonist for ionotropic glutamate receptors, has been accomplished. A key intermediate 15 was synthesized by two approaches. The first s
