949103-95-1Relevant academic research and scientific papers
A general approach to the synthesis of 1-deoxy-L-iminosugars
Guaragna, Annalisa,D'Errico, Stefano,D'Alonzo, Daniele,Pedatella, Silvana,Palumbo, Giovanni
, p. 3473 - 3476 (2007)
A stereoselective procedure for the preparation of non-naturally occurring deoxy iminosugars belonging to L-series has been developed. The synthesis involves the construction of the key intermediate bicycle pyperidine 8, available in few steps by the coup
A general route to D- and L-six-membered nucleoside analogues
Guaragna, Annalisa,D'Alonzo, Daniele,De Nisco, Mauro,Pedatella, Silvana,Palumbo, Giovanni
, p. 959 - 962 (2007)
A simple synthetic route for novel L-(as well as D-) six-membered nucleosides is described. Particularly, we have provided a general approach to the synthesis of azasugar-based nucleosides, which preparation has been easily achieved starting from the coup
Synthesis of 1-deoxy-l-gulonojirimycin and 1-deoxy-l-talonojirimycin
Guaragna, Annalisa,D'Alonzo, Daniele,Paolella, Concetta,Palumbo, Giovanni
scheme or table, p. 2045 - 2047 (2009/09/05)
De novo synthesis of noncompetitive glycosidase inhibitors l-gulo-DNJ and l-talo-DNJ has been achieved in 9-10 steps starting from Garner's aldehyde. Key to the success of this procedure was the construction of the 2,3-unsaturated piperidine 14, which syn
