94922-20-0Relevant academic research and scientific papers
PALLADIUM CATALYSED TANDEM CYCLISATION-ANION CAPTURE PROCESSES. HYDRIDE ION CAPTURE BY VINYLPALLADIUM SPECIES.
Burns, Barry,Grigg, Ronald,Sridharan, Visuvanathar,Worakun, Tanachat
, p. 4325 - 4328 (1988)
A new palladium catalysed-anion capture process is proposed.Examples are provided involving cyclisation of o-(ω-acetylenic)-aryl iodides and 2-bromo-1,6-enynes to heterocyclic- and carbocyclic-vinylpalladium species followed by hydride ion capture.
A rhodium catalyzed cycloisomerization and tandem Diels-Alder reaction for facile access to diverse bicyclic and tricyclic heterocycles
Zhou, Yirong,Nikbakht, Ali,Bauer, Felix,Breit, Bernhard
, p. 4805 - 4810 (2019/05/17)
A regioselective distal cycloisomerization of 1,6-allenenes was successfully developed to afford six-membered ring exocyclic 1,3-dienes employing a rhodium/diphosphine catalyst system. Deuterium labelling experiments and DFT calculations were performed to provide insights into the reaction mechanism of this unprecedented transformation. In addition, one-pot tandem Diels-Alder reactions with various dienophiles could readily construct diverse bicyclic and tricyclic nitrogen heterocycles, which are ubiquitous core scaffolds for a variety of natural products and bioactives. High efficiency and exclusive chemo and regioselectivities for a broad substrate scope were achieved under mild conditions using a low catalyst loading of 0.5 mol%.
REGIOSPECIFIC FORMATION OF 1,3-DIENES BY THE PALLADIUM CATALYSED INTRA- AND INTER-MOLECULAR COUPLING OF VINYL HALIDES
Grigg, Ronald,Stevenson, Paul,Worakun, Tanachat
, p. 2049 - 2054 (2007/10/02)
Palladium acetate (5 mol percent) effects catalytic inter and intra-molecular coupling of vinyl bromides in good yield under mild conditions provided sufficient triarylphosphine and potassium carbonate are present to regenerate the active palladium(0) spe
RHODIUM (1) CATALYSED REGIOSPECIFIC CYCLISATION OF 1,6-ENYNES TO METHYLENECYCLOHEX-2-ENES
Grigg, Ronald,Stevenson, Paul,Worakun, Tanachat
, p. 4967 - 4972 (2007/10/02)
1,6-Enynes are cyclised regiospecifically by 5 mol percent of Wilkinson's catalyst in acetonitrile at 80 deg C to give the corresponding methylenecyclohex-2-enes usually in goog yield (62-83percent).Terminal substitution on either the alkene
Rhodium- and Palladium-catalysed Formation of Conjugated Mono- and Bis-exocyclic Dienes. 5-Exo-Trig versus 6-Endo-Trig Cyclisations
Grigg, Ronald,Stevenson, Paul,Worakun, Tanachat
, p. 1073 - 1075 (2007/10/02)
2-Bromo-1,6-dienes are catalytically cyclised to give conjugated 5-membered bis-exocyclic dienes and 6-membered mono-exocyclic dienes by rhodium and palladium catalysts, the specificity for a 5- or 6-membered ring being a function of substrate, catalyst,
