94922-20-0Relevant academic research and scientific papers
PALLADIUM CATALYSED TANDEM CYCLISATION-ANION CAPTURE PROCESSES. HYDRIDE ION CAPTURE BY VINYLPALLADIUM SPECIES.
Burns, Barry,Grigg, Ronald,Sridharan, Visuvanathar,Worakun, Tanachat
, p. 4325 - 4328 (1988)
A new palladium catalysed-anion capture process is proposed.Examples are provided involving cyclisation of o-(ω-acetylenic)-aryl iodides and 2-bromo-1,6-enynes to heterocyclic- and carbocyclic-vinylpalladium species followed by hydride ion capture.
A rhodium catalyzed cycloisomerization and tandem Diels-Alder reaction for facile access to diverse bicyclic and tricyclic heterocycles
Zhou, Yirong,Nikbakht, Ali,Bauer, Felix,Breit, Bernhard
, p. 4805 - 4810 (2019/05/17)
A regioselective distal cycloisomerization of 1,6-allenenes was successfully developed to afford six-membered ring exocyclic 1,3-dienes employing a rhodium/diphosphine catalyst system. Deuterium labelling experiments and DFT calculations were performed to provide insights into the reaction mechanism of this unprecedented transformation. In addition, one-pot tandem Diels-Alder reactions with various dienophiles could readily construct diverse bicyclic and tricyclic nitrogen heterocycles, which are ubiquitous core scaffolds for a variety of natural products and bioactives. High efficiency and exclusive chemo and regioselectivities for a broad substrate scope were achieved under mild conditions using a low catalyst loading of 0.5 mol%.
RHODIUM (1) CATALYSED REGIOSPECIFIC CYCLISATION OF 1,6-ENYNES TO METHYLENECYCLOHEX-2-ENES
Grigg, Ronald,Stevenson, Paul,Worakun, Tanachat
, p. 4967 - 4972 (2007/10/02)
1,6-Enynes are cyclised regiospecifically by 5 mol percent of Wilkinson's catalyst in acetonitrile at 80 deg C to give the corresponding methylenecyclohex-2-enes usually in goog yield (62-83percent).Terminal substitution on either the alkene
REGIOSPECIFIC FORMATION OF 1,3-DIENES BY THE PALLADIUM CATALYSED INTRA- AND INTER-MOLECULAR COUPLING OF VINYL HALIDES
Grigg, Ronald,Stevenson, Paul,Worakun, Tanachat
, p. 2049 - 2054 (2007/10/02)
Palladium acetate (5 mol percent) effects catalytic inter and intra-molecular coupling of vinyl bromides in good yield under mild conditions provided sufficient triarylphosphine and potassium carbonate are present to regenerate the active palladium(0) spe
Rhodium- and Palladium-catalysed Formation of Conjugated Mono- and Bis-exocyclic Dienes. 5-Exo-Trig versus 6-Endo-Trig Cyclisations
Grigg, Ronald,Stevenson, Paul,Worakun, Tanachat
, p. 1073 - 1075 (2007/10/02)
2-Bromo-1,6-dienes are catalytically cyclised to give conjugated 5-membered bis-exocyclic dienes and 6-membered mono-exocyclic dienes by rhodium and palladium catalysts, the specificity for a 5- or 6-membered ring being a function of substrate, catalyst,
