94930-66-2Relevant academic research and scientific papers
Naphthopyranone synthesis via the tandem Michael-Dieckmann reaction of ortho-toluates with 5,6-dihydropyran-2-ones
Tan, Nichole P.H.,Donner, Christopher D.
, p. 4160 - 4162 (2008)
The tandem Michael-Dieckmann reaction between a series of ortho-toluates and the α,β-unsaturated lactone 25 is described. The tandem reaction delivers substituted naphthopyranones in moderate (20-49%) yields, whilst limitations in the tolerance of this reaction for different substituents on the ortho-toluate are identified. Crown Copyright
Synthesis of Functionalized Hydroxyphthalides and Their Conversion to 3-Cyano-1(3H)-isobenzofuranones. The Diels-Alder Reaction of Methyl 4,4-Diethoxybutynoate and Cyclohexadienes
Freskos, John N.,Morrow, Gary W.,Swenton, John S.
, p. 805 - 810 (2007/10/02)
Several methods have been used in the preparation of functionalized hydroxyphthalides.Metalation of N,N-diethyl-3-methoxybenzamide, followed by reaction with dimethylformamide and hydrolysis, furnished 3-hydroxy-4-methoxy-1(3H)-isobenzofuranone in 52perce
