94936-29-5

Basic information

• Product Name: methyl 3-benzyloxycarbonyl-7,8-dihydroxy-2-oxa-3,5-diazabicyclo<2.2.2>octane-5-carboxylate
• CAS NO: 94936-29-5
• Molecular Weight: 338.317
• Mol File: 94936-29-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 3-benzyloxycarbonyl-7,8-dihydroxy-2-oxa-3,5-diazabicyclo<2.2.2>octane-5-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-benzyloxycarbonyl-7,8-dihydroxy-2-oxa-3,5-diazabicyclo<2.2.2>octane-5-carboxylate(94936-29-5)
• EPA Substance Registry System: methyl 3-benzyloxycarbonyl-7,8-dihydroxy-2-oxa-3,5-diazabicyclo<2.2.2>octane-5-carboxylate(94936-29-5)

Safety Data

• Hazardous Substances Data: 94936-29-5(Hazardous Substances Data)

Upstream product

• 3426-71-9 Benzyl N-hydroxycarbamate 
• 33707-36-7 1-(methoxycarbonyl)-1,2-dihydropyridine 
• 88818-16-0 benzyl nitrosoformat 
• 94936-55-7 methyl 3-benzyloxycarbonyl-2-oxa-3,5-diazabicyclo<2.2.2>oct-7-ene-5-carboxylate 

Downstream Products

• 114217-88-8 methyl 3-benzyloxycarbonyl-7,8-diacetoxy-2-oxa-3,5-diazabicyclo<2.2.2>octane-5-carboxylate 

Relevant articles and documents

Syntheses of Diamino-dideoxylyxose Derivatives using Acylnitroso Dienophiles

N-Acylnitroso derivatives 6 which were prepared by in-situ oxidation of the corresponding hydroxamic acids 5 reacted instantaneously and in high yields with dihydropyridine 4.The Diels-Alder adducts 8 were formed regiospecifically with the acylnitroso dienophiles 6a-c, whereas the dienophiles 6d-f gave mixtures of both regioisomers 7 and 8.These and some other results were best explained by the FMO theory.The Diels-Alder adducts 7 and 8 gave the corresponding 'anti'-cis-glycols when reacted with OsO4/N-methylmorpholine N-oxide.Hydrogenolysis of the N-O bond folloved by peracetylation led to the expected aminolyxose derivatives 14 and 16.A similar sequence, using 4 and the hydroxamic-acid derivative 18 of (+)-D-mandelic acid led, with a poor assymmetric induction, to a mixture of the expected optically active aminolyxose compounds 19A/19B.