94938-02-0

Basic information

• Product Name: 1-METHYL-2-PHENYL-1H-IMIDAZOLE-4-CARBALDEHYDE
• Synonyms: 1-METHYL-2-PHENYL-1H-IMIDAZOLE-4-CARBALDEHYDE;1-methyl-2-phenyl-1H-imidazole-4-carboxaldehyde
• CAS NO: 94938-02-0
• Molecular Formula: C₁₁H₁₀N₂O
• Molecular Weight: 186.2099
• Mol File: 94938-02-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-METHYL-2-PHENYL-1H-IMIDAZOLE-4-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-METHYL-2-PHENYL-1H-IMIDAZOLE-4-CARBALDEHYDE(94938-02-0)
• EPA Substance Registry System: 1-METHYL-2-PHENYL-1H-IMIDAZOLE-4-CARBALDEHYDE(94938-02-0)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 94938-02-0(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of Medicinal Chemistry, 29, p. 261, 1986 DOI: 10.1021/jm00152a015

Upstream product

• 99280-78-1 (1-methyl-2-phenyl-1H-imidazol-4-yl)methanol 
• 77-78-1 dimethyl sulfate 
• 68282-47-3 2-phenyl-1H-imidazole-4-carbaldehyde 
• 74-88-4 methyl iodide 
• 616-38-6 carbonic acid dimethyl ester 
• 100-47-0 benzonitrile 
• 43002-54-6 (2-phenyl-1H-imidazol-4-yl)-methanol 

Downstream Products

• 851182-97-3 bis[(1-methyl-2-phenyl-4-imidazolyl)methyl]benzylamine 
• 851182-98-4 bis[(1-methyl-2-phenyl-4-imidazolyl)methyl]amine 

Relevant articles and documents

Copper-catalyzed intramolecular dehydrogenative aminooxygenation: Direct access to formyl-substituted aromatic N-heterocycles

A direct synthesis of carbaldehydes through intramolecular dehydrogenative aminooxygenation has been developed. The process uses a catalytic amount of copper(II) in DMF or DMA under oxygen and does not require additional oxidants (see scheme). Mechanistic studies suggest that the carbonyl oxygen atom of the aldehyde is derived from oxygen through a copper-mediated oxygen activation process via a peroxy-copper(III) intermediate. Copyright

PIPERIDINE-CONTAINING COMPOUNDS AND USE THEREOF

A method for preventing and/or treating a metabolic disease, cerebrovascular disease, etc. which comprises administering to a mammal an effective amount of the compound of the formula (I) wherein all symbols have the same meanings as defined in the specification; a salt thereof, an N-oxide thereof, a solvate thereof, or a prodrug thereof. And a novel compound of the formula (I-1): wherein all symbols have the same meanings as defined in the specification; a salt thereof, an N-oxide thereof, a solvate thereof, or a prodrug thereof has an anti-diabetic effect and a neuroprotective effect. Accordingly, the compound of the formula (I) and the compound of the formula (I-1) are useful in a method for preventing and/or treating for a metabolic disease such as diabetes, cerebrovascular disease such as stroke, etc.

Synthesis and reactivity of a (μ-1,1-hydroperoxo)(μ-hydroxo) dicopper(II) complex: Ligand hydroxylation by a bridging hydroperoxo ligand

A new tetradentate tripodal ligand (L3) containing sterically bulky imidazolyl groups was synthesized, where L3 is tris(1-methyl-2-phenyl-4- imidazolylmethyl)amine. Reaction of a bis(μ-hydroxo)dicopper(II) complex, [Cu2(L3)2(OH)

Synthesis, structure, and neuroprotective properties of novel imidazolyl nitrones

A new series of imidazolyl nitrones spin traps has been synthesized and evaluated pharmacologically. The salient structural feature of these molecules is the presence of an imidazole moiety substituted by aromatic or heteroaromatic cycles. This connectivi