949489-26-3

Upstream product

• 25878-60-8 D-galactose pentaacetate 
• 4163-60-4 β-D-galactose peracetate 
• 106-45-6 para-thiocresol 
• 28244-94-2 4-methylphenyl 2,3,4,6-tetra-O-acetyl-1-thio-β-D-galactopyranoside 
• 1152-39-2 p-methylphenyl-1-thio-β-D-galactopyranoside 
• 824-94-2 p-methoxybenzyl chloride 

Downstream Products

• 949489-27-4 p-tolyl 2,4,6-tri-O-benzyl-3-O-(p-methoxybenzyl)-1-thio-β-D-galactopyranoside 
• 1447700-78-8 (2R,3S,4S,5R,6R)-2-(acetoxymethyl)-6-(5-(benzyloxycarbonylamino)pentyloxy)-4-(4-methoxybenzyloxy)tetrahydro-2H-pyran-3,5-diyl diacetate 
• 1447700-80-2 benzyl N-benzyl-N-(5-((2R,3R,4S,5R,6R)-3,5-bis(benzyloxy)-6-(benzyloxymethyl)-4-hydroxytetrahydro-2H-pyran-2-yloxy)pentyl)carbamate 
• 1447700-79-9 benzyl N-benzyl-N-(5-((2R,3R,4S,5S,6R)-3,5-bis(benzyloxy)-6-(benzyloxymethyl)-4-(4-methoxybenzyloxy)tetrahydro-2H-pyran-2-yloxy)pentyl)carbamate 
• 949489-25-2 p-tolyl 2,4,6-tri-O-benzyl-1-thio-β-D-galactopyranoside 

Relevant academic research and scientific papers

COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS

Compositions and methods for the treatment of bacterial infections include compounds containing dimers of cyclic heptapeptides conjugated to one or more monosaccharide or oligosaccharide moieties. In particular, compounds can be used in the treatment of bacterial infections caused by Gram-negative bacteria.

CARBOHYDRATE-MODIFIED GLYCOPROTEINS AND USES THEREOF

The present invention provides immunogenic compounds which stimulate immune responses in a subject. The present invention provides compositions comprising an isolated glycoprotein antigen covalently bound at pre-existing carbohydrate residues present on the glycoprotein to a carbohydrate epitope. The present invention also provides a method to induce an immune response in a subject comprising administering the compounds of the invention. The present invention further provides methods of making the compounds of the invention and methods of using the compounds of the invention to stimulate immune responses to infectious disease agents and tumors.

Structural establishment of polygalatenosides A and B by total synthesis

The first total synthesis of polygalatenosides A (1) and B (2), originally isolated from the traditional Chinese medicine and reported as antidepressant agents, is described here. Glycosylation between thiogalactosyl donors 6 and 7 and 1-deoxyglucosyl acc

Multi-component one-pot synthesis of the tumor-associated carbohydrate antigen globo-H based on preactivation of thioglycosyl donors

(Chemical Equation Presented) Two efficient routes for the rapid assembly of the tumor-associated carbohydrate antigen Globo-H hexasaccharide 2 by a preactivation based iterative one-pot strategy are reported. The first method involves the sequential coup