949493-62-3

Upstream product

• 1332506-72-5 (2S,1'S)-tert-butyl(dimethyl)(2-(1'-(phenyl)allyloxy)but-3-enyloxy)silane 
• 369-57-3 benzenediazonium tetrafluoroborate 

Downstream Products

• 949573-15-3 (2S,4S,5S,3R)-2-hydroxymethyl-5-phenyltetrahydro-3,4-furandiol 
• 607376-15-8 ethyl 3-[2,2-dimethyl-6-phenyl-(3aS,4R,6R,6aR)-perhydrofuro[3,4-d][1,3]dioxol-4-yl]-(Z)-2-propenoate 
• 949493-64-5 (4S,6S,6aS,3aR)-2,2-dimethyl-6-phenylperhydrofuro[3,4-d][1,3]dioxol-4-ylmethanol 

Relevant academic research and scientific papers

A modular approach to aryl-C-ribonucleosides via the allylic substitution and ring-closing metathesis sequence. A stereocontrolled synthesis of all four α-/β- and D-/L-C-nucleoside stereoisomers

Iridium(I)-catalyzed allylation of the enantiopure monoprotected copper(I) alkoxide, generated from (S)-5a, with the enantiopure allylic carbonates (R)-9a,b has been developed as the key step in a new approach to C-nucleoside analogues. The anomeric cente

Stereoselective Heck-Matsuda arylations of chiral dihydrofurans with arenediazonium tetrafluoroborates; an efficient enantioselective total synthesis of (-)-isoaltholactone

The Heck-Matsuda arylation of chiral 2-(S)-hydroxymethyl dihydrofurans (endocyclic enolethers) and its derivatives, employing arenediazonium tetrafluoroborates, was developed into a highly efficient, practical and diastereoselective synthetic process. This methodology was applied to the total synthesis of the styryllactone (-)-isoaltholactone in seven steps with an overall yield of ～25%, from the readily available chiral 2-hydroxymethyldihydrofuran. The strategy permits the synthesis of several other aromatic analogues of isoaltholactone. Georg Thieme Verlag Stuttgart.