949573-15-3

Upstream product

• 949493-62-3 (-)-2',3'-didehydro-1',2',3'-trideoxy-1'-phenyl-α-D-ribofuranose 

Downstream Products

• 949493-64-5 (4S,6S,6aS,3aR)-2,2-dimethyl-6-phenylperhydrofuro[3,4-d][1,3]dioxol-4-ylmethanol 
• 607376-15-8 ethyl 3-[2,2-dimethyl-6-phenyl-(3aS,4R,6R,6aR)-perhydrofuro[3,4-d][1,3]dioxol-4-yl]-(Z)-2-propenoate 

Relevant academic research and scientific papers

Stereoselective Heck-Matsuda arylations of chiral dihydrofurans with arenediazonium tetrafluoroborates; an efficient enantioselective total synthesis of (-)-isoaltholactone

The Heck-Matsuda arylation of chiral 2-(S)-hydroxymethyl dihydrofurans (endocyclic enolethers) and its derivatives, employing arenediazonium tetrafluoroborates, was developed into a highly efficient, practical and diastereoselective synthetic process. This methodology was applied to the total synthesis of the styryllactone (-)-isoaltholactone in seven steps with an overall yield of ～25%, from the readily available chiral 2-hydroxymethyldihydrofuran. The strategy permits the synthesis of several other aromatic analogues of isoaltholactone. Georg Thieme Verlag Stuttgart.