95-09-0

Usage

Uses

Used in Organic Synthesis:
5-(chloromethyl)bicyclo[2.2.1]hept-2-ene is used as a key intermediate in organic synthesis for the creation of various organic compounds. Its reactivity allows for the formation of new chemical bonds and the synthesis of complex molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 5-(chloromethyl)bicyclo[2.2.1]hept-2-ene is used as a building block for the synthesis of pharmaceuticals. Its unique structure and reactivity contribute to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
5-(chloromethyl)bicyclo[2.2.1]hept-2-ene is also utilized in the agrochemical industry as a precursor for the synthesis of agrochemicals. Its incorporation into these products can enhance their effectiveness in agricultural applications.
Used as a Reagent in Chemical Reactions:
5-(chloromethyl)bicyclo[2.2.1]hept-2-ene is used as a reagent in various chemical reactions, facilitating the formation of desired products and aiding in the advancement of chemical research and development.
Overall, 5-(chloromethyl)bicyclo[2.2.1]hept-2-ene is a versatile and valuable compound in the field of organic chemistry, with applications spanning across different industries, including pharmaceuticals and agrochemicals. Its proper handling and use are essential to ensure safety and maximize its potential in creating beneficial chemical products.

Upstream product

• 95-12-5 5-hydroxymethyl-2-norbornene 
• 77-73-6 bi(cyclopentadiene) 
• 107-05-1 3-chloroprop-1-ene 
• 15507-06-9 5-norbornene-2-methanol 
• 542-92-7 cyclopenta-1,3-diene 

Downstream Products

• 5549-09-7 bicyclo[3.3.0]oct-2-ene 
• 823-02-9 bicyclo[3.2.1]oct-2-ene 
• 765-99-1 4-allylcyclopentene 
• 14564-97-7 3-allyl-1-cyclopentene 
• 822-96-8 5-methyl-2-norbornene 
• 822-96-8 5-methylbicyclo[2.2.1]heptan-2-ene 
• 29378-03-8 1-allyl-1,3-cyclopentadiene 
• 765-90-2 (+/-)-2endo-methyl-norbornane 
• 1007-01-8 endo-2-bicyclo<2.2.1>heptylacetic acid 
• 16002-26-9 Essigsaeure-<8,9,10-trinorbornan-2-endo-methyl>ester 

Relevant academic research and scientific papers

Versatile route to functionalized vinylic addition polynorbornenes

Vinylic addition polynorbornenes bearing functional groups can be obtained in a versatile way by nucleophilic substitution of a halogen in new vinylic haloalkyl polynorbornenes. The latter are obtained by vinylic homo and copolymerization of norbornene and haloalkyl norbornenes catalyzed by [Ni(C 6F5)2(SbPh3)2]. This method circumvents the problem of catalyst deactivation encountered in classical copolymerizations with polar monomers. The content of substituted monomer in the copolymers is in the range 26-59%, depending on the monomer ratio in the feed. Nucleophilic substitution reactions afford polymers with ester, cyano, phenylthio, or azido groups in the same wide range of composition. Click chemistry on the azido polynorbornenes give polynorbornenes with pendant triazole groups.

Preparation and functionalisation of emulsion-derived microcellular polymeric foams (polyHIPEs) by ring-opening metathesis polymerisation (ROMP)

Emulsion-derived microcellular polymeric foams (poly-HIPEs) have been prepared by ring opening metathesis polymerisation of a norbornene derivative using a Grubb's catalyst. The resulting material has been further function-alised using the active catalytic sites remaining on its structure.

Synthesis of Organosilanes and Oligoorganosiloxanes by Hydrosilylation of Halomethyl Derivatives of Bicyclo[2.2.1]hept-5-ene

The reaction of halomethyl derivatives of bicyclo[2.2.1]hept-5-ene with dimethylphenylsilane and oligodimethylsiloxanes HSiMe2[OSiMe2]nH (n = 1-3) and CH3(CH2)3SiMe2[OSiMe 2]25H was investigated. Unlike hydrosilylation of allyl halides, the yields of the addition products in the studied system reach 85%.

Imidazole derivatives and salts thereof and pharmaceutical formulations useful in thrombo-embolic disorders

Imidazoles of formula (I) STR1 wherein A is a chemical bond or a straight or branched, saturated or unsaturated, aliphatic residue having from 1 to 6 carbon atoms wherein 1, 2 or 3 of such carbon atoms may be replaced by a corresponding number of heteroatoms selected from oxygen, sulphur and nitrogen providing (in the case of 2 or 3 heteroatoms) that any such heteroatom is not located adjacent to a further such heteroatoms or heteroatoms R is a fused, saturated or unsaturated, non-aromatic carbocyclic, polycyclic ring system; a saturated or unsaturated, carbocyclic spirocyclic ring system, optionally containing one or more ring heteroatoms selected from oxygen, sulphur and nitrogen; or a saturated or unsaturated, carbocyclic bridged-polycyclic ring system, optionally containing one or more ring heteroatoms selected from oxygen, sulphur and nitrogen and having one or more bridges; or AR together represent a straight or branched, saturated or unsaturated, aliphatic residue having 3 to 6 carbon atoms, wherein 1, 2 or 3 of such carbon atoms may be replaced by a corresponding number of heteroatoms selected from oxygen, sulphur and nitrogen providing (in the case of 2 or 3 heteroatoms) that any such heteroatom is not located adjacent to a further such heteroatom or heteroatoms; which aliphatic residue is substituted by at least two groups, which may be the same or different, selected from the groups specified for R above. and acid addition salts and pharmaceutically acceptable bioprecursors thereof. Methods of preparing the imidazoles are disclosed. The imidazoles and their acid addition salts and bioprecursors are useful in the treatment or prophylaxis of thrombo-embolic conditions.