950-59-4

Usage

Uses

A possible inhibitor of DNA-benzo[a]pyrene adducts formation and benzopyrene activation.

InChI:InChI=1/C14H22OS/c1-13(2,3)10-7-9(16)8-11(12(10)15)14(4,5)6/h7-8,15-16H,1-6H3

Upstream product

• 6386-58-9 4,4'-dithiobis(2,6-di-tert-butylphenol) 
• 3957-71-9 3,5-di-tert-butyl-4-hydroxyphenylthiocyanate 
• 128-39-2 2,6-di-tert-butylphenol 

Downstream Products

• 55485-65-9 <1-Hydroxy-2,6-di-tert.-butyl-phenyl-(4)>-essigsaeurethiolester 
• 26532-81-0 4-tert.-Butylmercapto-2,6-di-tert.-butyl-phenol 
• 14156-46-8 4-(Diphenylphosphinylthio)-2,6-di-tert.-butylphenol 
• 103627-66-3 α-(3,5-di-tert-butyl-4-hydroxyphenylthio)-γ-butyrolactone 
• 92176-73-3 3-(3,5-di-t-butyl-4-hydroxyphenylthio)-1-methylpyrrolidine-2,5-dione 
• 100204-33-9 3,5-di-tert-butyl-4-hydroxyphenyl S-(hydroxymethyl) sulfide 
• 92176-79-9 3-(3,5-di-t-butyl-4-hydroxyphenylthio)-1-cyclohexylpyrrolidine-2,5-dione 
• 143745-66-8 2,6-bis(1,1-dimethylethyl)-4-<<2-(phenylamino)ethyl>thio>phenol 
• 2455-14-3 3,5,3',5'-tetra-tert-butyl-4,4'-diphenoquinone 
• 81539-15-3 bis(2,6-di-tert-butyl-4-mercaptophenolato)cobalt 
• 81539-16-4 bis(2,6-di-tert-butyl-4-mercaptophenolato)nickel 
• 92176-76-6 1,2-bis<3-(3,5-di-t-butyl-4-hydroxyphenylthio)-2,5-dioxopyrrolidin-1-yl>benzene 
• 92176-74-4 1,4-bis<3-(3,5-di-t-butyl-4-hydroxyphenylthio)-2,5-dioxopyrrolidin-1-yl>benzene 
• 105648-40-6 <3,5-di(tert-butyl)>-4-hydroxyphenylthioacetic acid nitrile 

Relevant academic research and scientific papers

Synthesis method of dithiobis-butyl phenol and analogue thereof

The invention provides a synthesis method of dithiobis-butyl phenol and an analogue thereof. The synthesis method provided by the invention has the advantages of few steps, high yield and high purity of the obtained product. The dithiobis-butyl phenol and the analogue thereof synthesized by the invention can be used for preparing medicines for preventing and/or treating coronavirus pneumonia (containing COVID-19).

Probucol derivative, preparation method and application thereof

The invention relates to the fields of compounds, and specifically relates to a probucol derivative, a preparation method and the application thereof. The probucol derivative has a structure shown asa general formula I. The probucol derivative provided by the invention can be used for prevention and curing of vascular diseases such as diabetes and cardiovascular and cerebrovascular diseases or complications thereof, can be used for reducing blood glucose, reducing blood fat, reducing cholesterol, reducing the weight, reducing triglyceride, resisting inflammation and oxidation and the like effectively, and has a wide application prospect.

Chemo- and product-selective electrooxidation of 3-(arylthiomethyl)- Δ3-cephems

Electrolysis of 3-arylthiomethyl-Δ3-cephems possessing various substituents on the arylthio moiety undergo chemo selective and product-selective electrooxidation to give several different products. These include isomeric mixtures of the corresponding methoxylated cephems, a bis[(Δ3-cephem-3-yl)methyl]disulfide or a 3-dimethoxymethyl- Δ3-cephem. The selectivity of the oxidation is highly dependent on the nature of the substituents on the arylthio moiety which suggests that both steric and electronic effects play an important role in the electrooxidation of 3-arylthiomethyl-Δ3-cephems.

METHODS FOR PRODUCING 2,6-DI-TERT-BUTYL-4-MERCAPTOPHENOL AND 4,4'-ISOPROPYLIDENEDITHIOBIS[2,6-DI-TERT-BUTYLPHENOL]

The present invention provides a method for producing 2,6-di-tert-butyl-4-mercaptophenol containing reducing bis(3,5-di-tert-butyl-4-hydroxyphenyl) polysulfide with zinc in a mixed solvent of toluene and n-butanol, and provides a method for producing 4,4'-isopropylidenedithiobis[2,6-di-tert-butylphenol] using the above-mentioned method.

COMPOSITIONS AND METHODS FOR TREATING CARDIOVASCULAR DISORDERS

The present invention relates to compounds and methods for the treatment of cardiovascular diseases and disorders. Compounds according to the present invention may comprise an optionally substituted phenyl ring linked to an aromatic or alkyl group by a spacer, wherein the spacer comprises two groups selected from selenium, sulfur, S(O) and S(O)2 and may further optionally comprise an alkylene, alkenylene, cycloalkylene or arylene moiety between the respective selenium, sulfur, S(O) and S(O)2 groups.

Mechanism of the antioxidative effect of bis(4-hydroxy-3,5-di-tert-butylphenyl) sulfide and polysulfides in cumene oxidation

Bis(4-hydroxy-3,5-di-tert-butylphenyl) sulfide and polysulfides were prepared, and their inhibiting power was studied in relation to the number of sulfur atoms.

Antioxidant and cholesterol lowering properties of 2,6-di-t-butyl-4- [(dimethylphenylsilyl)methyloxy]phenol and derivatives: A new class of anti- atherogenic compounds

Di-t-butylphenol derivatives were synthesized and evaluated as antioxidants and cholesterol lowering agents. When evaluated in cholesterol- fed rabbits, the compounds were found to exhibit both properties. Of special interest was the finding that several of the compounds elevated HDL cholesterol levels.

Phenolic thioetheramides

The present invention relates to phenolic thioetheramides of the formula STR1 wherein R1 and R2 are tert-alkyl or phenyl, Alk1 and Alk2 are alkylene; X is sulfur or oxygen, m is 0, 1, or 2; and R is STR2 wherein R3 and R4 are hydrogen or alkyl and Alk3 is alkylene.

2-AMINOETHANESULFONIC ACID DERIVATIVES OF 3,5-DISUBSTITUTED-4-HYDROXY-PHENOLIC THIOETHERS

The present invention relates to compounds of the Formula I:wherein R1 and R2 are the same or different and independently represent tert-alkyl, halogen, or phenyl; Alk 1 represents straight or branched chain alkylene of 2 to 10 carbon atoms which can optionally be substituted by hydroxy, provided that said hydroxy is not attached to a carbon which is adjacent to sulfur or oxygen, X represents sulfur or oxygen, and Alk 2 represents straight or branched chain alkylene of 1 to 4 carbon atoms; and the pharmaceutically acceptable salts thereof. These compounds are specific 5-lipoxygenase inhibitors and are useful as anti-inflammatory and anti-allergy agents and in the treatment of conditions mediated by 5-lipoxygenase