95043-91-7Relevant academic research and scientific papers
Enantio- and diastereoselective reductive aldol reactions with iridium-pybox catalysts
Zhao, Cun-Xiang,Duffey, Matthew O.,Taylor, Steven J.,Morken, James P.
, p. 1829 - 1831 (2007/10/03)
(formula presented) A catalytic amount of [(cod)IrCl]2 and indane-pybox converts diethylmethylsilane, methyl acrylate, and certain aldehydes to the derived reductive aldol adduct with good enantio- and diastereocontrol.
Synthesis of propionate motifs: Diastereoselective tandem reactions involving anionic and free radical based processes
Guindon,Houde,Prevost,Cardinal-David,Landry,Daoust,Bencheqroun,Guerin
, p. 8496 - 8501 (2007/10/03)
Reported herein is a strategy employing a Mukaiyama reaction in tandem with a hydrogen transfer reaction for the elaboration of propionate motifs. The nature of the protecting groups on the chiral β-alkoxy aldehyde and the type of Lewis acid used are vari
Stereo-Modulating Catalysis by Europium(III) Complexes in Aldol Reactions of Chiral α-Alkoxy Aldehydes with Ketene Silyl Acetals
Terada, Masahiro,Gu, Jin-Hua,Deka, Dibakar C.,Mikami, Koichi,Nakai, Takeshi
, p. 29 - 32 (2007/10/02)
The Eu(fod)3- or Eu(dppm)3-catalyzed aldol reactions of the four chiral α-alkoxy aldehydes having different protecting groups with (E)- or (Z)-ketene silyl acetals are shown to provide the high levels of diasterocontrol, the sense depending on the nature
ALDOL ADDITIONS to α- AND β-ALKOXY ALDEHYDES : THE EFFECT OF CHELATION ON SIMPLE DIASTEREOSELECTIVITY
Reetz, M. T.,Kesseler, K.,Jung, A.
, p. 4327 - 4336 (2007/10/02)
The TiCl4 or SnCl4 mediated reaction of enol silanes with chiral α- or β-alkoxy aldehydes constitutes the only presently known, general way to perform aldol additions with chelation-control (asymmetric induction >90percent).If the enol silane is prochiral
