34880-70-1

Basic information

• Product Name: 1-METHOXY-1-TRIMETHYLSILYLOXYPROPENE
• Synonyms: 1-METHOXY-1-TRIMETHYLSILYLOXYPROPENE;[(1-METHOXY-1-PROPENYL)OXY]TRIMETHYLSILANE;Methoxytrimethylsilyloxypropene;1-METHOXY-1-TRIMETHYLSILYLOXYPROPENE 95+%;1-(Trimethylsiloxy)-1-methoxy-1-propene;Methylketene methyl(trimethylsilyl)acetal;Trimethyl(1-methoxy-1-propenyloxy)silane;(E)-((1-Methoxyprop-1-en-1-yl)oxy)triMethylsilane
• CAS NO: 34880-70-1
• Molecular Formula: C₇H₁₆O₂Si
• Molecular Weight: 160.29
• Product Categories: Monoalkoxysilanes;Protection & Derivatization Reagents (for Synthesis);Si (Classes of Silicon Compounds);Si-O Compounds;Synthetic Organic Chemistry;Vinylsilanes, Allylsilanes
• Mol File: 34880-70-1.mol

Chemical Properties

• Boiling Point: 52 °C / 27mmHg
• Flash Point: 23.505°C
• Appearance: /
• Density: 0.87
• Vapor Pressure: 9.805mmHg at 25°C
• Refractive Index: 1.4130-1.4160
• Storage Temp.: 0-10°C
• CAS DataBase Reference: 1-METHOXY-1-TRIMETHYLSILYLOXYPROPENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-METHOXY-1-TRIMETHYLSILYLOXYPROPENE(34880-70-1)
• EPA Substance Registry System: 1-METHOXY-1-TRIMETHYLSILYLOXYPROPENE(34880-70-1)

Safety Data

• RIDADR: 1993
• HazardClass: 3
• PackingGroup: III
• Hazardous Substances Data: 34880-70-1(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
1-Methoxy-1-trimethylsilyloxypropene is used as a building block in organic synthesis for its ability to undergo various transformations, leading to the creation of different organic products. Its stability and reactivity make it a preferred choice for constructing complex molecular structures.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 1-Methoxy-1-trimethylsilyloxypropene is utilized as a key intermediate for the synthesis of various pharmaceuticals. Its role in creating a wide range of organic molecules contributes to the development of new drugs and medicinal compounds.
Used in Agrochemical Industry:
1-Methoxy-1-trimethylsilyloxypropene is also employed in the agrochemical industry as a reagent in the preparation of agrochemicals. Its versatility in organic synthesis aids in the production of effective and innovative agricultural chemicals.
Used in Materials Science:
In the field of materials science, 1-Methoxy-1-trimethylsilyloxypropene is used as a component in the development of new materials. Its chemical properties allow for the creation of materials with specific characteristics, useful in various applications.

InChI:InChI=1/C7H16O2Si/c1-6-7(8-2)9-10(3,4)5/h6H,1-5H3/b7-6+

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 554-12-1 propanoic acid methyl ester 

Downstream Products

• 5634-53-7 methyl pyruvate oxime 
• 77086-39-6 methyl 2-(3-trimethylsiloxycyclohex-2-enyl)propionate 
• 77086-39-6 3,1'-syn-3-<1'-(carbomethoxy)ethyl>-1-<(trimethylsilyl)oxy>-1-cyclohexene 
• 77086-39-6 3,1'-anti-3-<1'-(carbomethoxy)ethyl>-1-<(trimethylsilyl)oxy>-1-cyclohexene 
• 113107-60-1 dimethyl 2,5-dimethyl-3-(phenylthio)adipate 
• 125742-11-2 (Z)-2,3-Dimethyl-5-phenyl-5-trimethylsilanyloxy-pent-4-enoic acid methyl ester 
• 88517-40-2 3-Benzyloxyamino-2-methyl-propionic acid methyl ester 
• 127376-13-0 2-{2-[2-(4-Methoxy-2-oxo-cyclohex-3-enyl)-ethyl]-[1,3]dioxolan-2-yl}-propionic acid methyl ester 
• 77086-43-2 methyl 2-(1,3-diphenyl-3-trimethylsiloxyprop-2-enyl)propionate 
• 57956-39-5 3-hydroxy-2-methyl-3-phenylbutyric acid methyl ester 
• 798568-63-5 2-cyclohexylidene-1-methoxy-3-methyl-1-trimethylsilyloxycyclopropane 
• 1025765-44-9 methyl 3-(1-(4-fluorophenyl)-1H-indazol-5-yl)-2-methyl-3-phenylpropanoate 
• 474744-52-0 Methyl 2-methyl-3-phenyl-3-(p-tolylsulfonylamino)propanoate 
• 54541-41-2 methyl 2-methyl-3-phenylbutanoate 

Relevant articles and documents

Synthesis and isolation of α-oxo sulfines

The synthesis of several α-oxo sulfines is discribed. Various α-oxo sulfines can be isolated as such. The Diels-Alder reaction of these sulfines with 1,3-dienes can be catalyzed by Lewis acids.

B(C6F5)3-Catalyzed C-H Alkylation of N-Alkylamines Using Silicon Enolates without External Oxidant

An efficient method for the coupling of N-alkylamines with silicon enolates to generate β-amino carbonyl compounds is disclosed. These reactions proceed by activation of α-amino C-H bonds by B(C6F5)3, which likely generate

Regioselective carboindation of simple alkenes with indium tribromide and ketene silyl acetals

(Equation Presented). The regioselective carboindation of simple alkenes with indium tribromide and ketene silyl acetals was accomplished. Various alkenes such as ethylene, 1-alkenes, and cyclic alkenes were applicable for this reaction system. The alkyli

Catalytic enantioselective aldol reaction to ketones

An enantioselective aldol reaction between ketones and ketene silyl acetals is described using CuF-chiral phosphine as a catalyst. The key for high enantioselectivity was the development of a novel ligand derived from Taniaphos combined with the unique ac

Surface-mediated solid phase reaction. Part 9. A convenient procedure for aldol reaction of ketene silyl acetals with aldehydes on the solid surface of alumina

The aldol reaction of ketene silyl acetals with aldehydes proceeds efficiently on the solid surface of alumina impregnated with anhydrous zinc chloride under sonication providing aldol products in high yields and with good stereoselectivity.

1,3-Dithienium- and 1,3-Dithiolenium Salts, III. Synthesis of Cyclic Dithioacetals of β-Keto Esters from Ketene Silyl Acetals

The 1,3-dithian-2-ylium tetrafluoroborates 3, available by different methods, react in good yields with the ketene silyl acetals 2 to give the new cyclic dithioacetals 4 which are deacetalized to the β-keto esters 5 and 9.

Reaction of Ketene Silyl Acetals with Diazonium Salts: a Novel α-Amino Acid Ester Synthesis

The reaction of ketene silyl acetals with arenediazonium tetrafluoroborate gave α-hydrazono and α-azo esters, which were easily hydrogenated to α-amino esters.

Keten Silyl Acetal Chemistry; Simple Synthesis of Methyl Jasmonate and Related Compounds by Utilising Keten Methyl Dimethyl-t-butylsilyl Acetal

Conjugate addition of keten silyl acetals to α,β-unsaturated carbonyl compounds in acetonitrile gave a quantitative yield of the corresponding methyl (3-trialkylsiloxyalk-2-enyl)acetates; subsequent site-specific electrophilic substitution yielded the corresponding 2-substituted 3-(alkoxycarbonylmethyl)alkanones.These novel addition and sequential alkylation reactions could be applied to a simple synthesis of methyl jasmonate, methyl didehydrojasmonate, and methyl dihydrojasmonate.