950489-40-4Relevant academic research and scientific papers
Preparation of enantiopure 3,5,5-trialkyl-γ-butyrolactones by diastereospecific 5-endo halo lactonizations
Garnier, Jean-Marc,Robin, Sylvie,Guillot, Regis,Rousseau, Gerard
, p. 1434 - 1442 (2008/02/11)
A new preparation of 3,5,5-trialkyl-γ-butyrolactones of defined absolute configuration is reported. This method involves the diastereoselective alkylation of 3,4-ethylenic acids after incorporation of a chiral Evans auxiliary, and then after separation of
