950525-67-4

Upstream product

• 108593-44-8 methyl 3-methoxy-5-methylbenzoate 
• 14001-63-9 2-methylthio-4-methylpyrimidine 
• 585-81-9 3-hydroxy-5-methylbenzoic acid 
• 950525-69-6 1-(3-methoxy-5-methylphenyl)-2-[2-methylsulfanylpyrimidin-4-yl)ethanone 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 

Downstream Products

• 1262110-33-7 [3-(3-methoxy-5-methylphenyl)-4-(2-methylthio-pyrimidin-4-yl)-pyrazol-1-yl]acetonitrile 
• 1262110-34-8 [4-(2-methanesulfonylpyrimidin-4-yl)-3-(3-methoxy-5-methylphenyl)-pyrazol-1-yl]acetonitrile 
• 1262110-37-1 [4-[2-(3(S)-hydroxypyrrolidin-1-yl)-pyrimidin-4-yl]-3-(3-methoxy-5-methylphenyl)-pyrazol-1-yl]acetonitrile 
• 1262110-38-2 [4-[2-(3(S)-hydroxypyrrolidin-1-yl)-pyrimidin-4-yl]-3-(3-hydroxy-5-methylphenyl)-pyrazol-1-yl]acetonitrile 
• 1262110-35-9 [4-[2-(3-hydroxyazetidin-1-yl)-pyrimidin-4-yl]-3-(3-methoxy-5-methylphenyl)-pyrazol-1-yl]acetonitrile 
• 1262110-36-0 [4-[2-(3-hydroxyazetidin-1-yl)-pyrimidin-4-yl]-3-(3-hydroxy-5-methylphenyl)-pyrazol-1-yl]acetonitrile 

Relevant academic research and scientific papers

Design, Synthesis, and In Vitro Cytotoxic Activity of Certain 2-[3-Phenyl-4-(pyrimidin-4-yl)-1H-pyrazol1-yl]acetamide Derivatives

Abstract: With a view to finding new anticancer agents, different aryloxy groups wereattached to C2 of the pyrimidine ring in2-[3-phenyl-4-(pyrimidin-4-yl)-1H-pyrazol-1-yl]acetamide in five steps using methyl3-methoxy-5-methylbenzoate as the ke

PYRAZOLE COMPOUNDS WITH INHIBITORY ACTIVITY AGAINST ROS KINASE

Disclosed herein are novel pyrazole compounds, pharmaceutically acceptable salts thereof, a method for preparing the same, and uses thereof as anticancer agents.

PYRAZOLE COMPOUNDS

The present invention is directed to compounds of Formula (I), and to salts and solvates thereof, their synthesis, and their use as Raf inhibitors.