950588-69-9Relevant articles and documents
Total synthesis and absolute configuration of koshikalide
Kunifuda, Kazuki,Iwasaki, Arihiro,Nagamoto, Masashi,Suenaga, Kiyotake
, p. 3121 - 3123 (2016)
The first total synthesis of koshikalide, a 14-membered macrolide that contains three olefins, was achieved. The skipped diene in the cyclic system was efficiently constructed by very mild Stille coupling at low temperature. The absolute stereochemistry was established by comparison of the specific optical rotations of natural and synthesized koshikalide.
Total synthesis of solandelactones E and F, homoeicosanoids from the hydroid Solanderia secunda
White, James D.,Martin, William H.C.,Lincoln, Christopher,Yang, Jongtae
, p. 3481 - 3483 (2008/02/12)
Asymmetrie total syntheses of solandelactones E and F confirmed that hydroxyl configuration at C11 in these oxylipins had been misassigned and that the stereochemistry at this center should be reversed. Key steps in the synthesis involved a Nagao asymmetr
