Tetrahedron Letters p. 3121 - 3123 (2016)
Update date:2022-08-05
Topics: Enantioselective Total synthesis Stereoselective Chiral Auxiliary Absolute Configuration
Kunifuda, Kazuki
Iwasaki, Arihiro
Nagamoto, Masashi
Suenaga, Kiyotake
The first total synthesis of koshikalide, a 14-membered macrolide that contains three olefins, was achieved. The skipped diene in the cyclic system was efficiently constructed by very mild Stille coupling at low temperature. The absolute stereochemistry was established by comparison of the specific optical rotations of natural and synthesized koshikalide.
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Doi:10.1002/ejic.200600546
(2006)Doi:10.1021/jo071009n
(2007)Doi:10.1246/bcsj.67.1113
(1994)Doi:10.1016/S0040-4039(01)91302-4
(1984)Doi:10.1016/j.carres.2007.05.009
(2007)Doi:10.1021/jo01025a039
(1964)
