95062-70-7Relevant academic research and scientific papers
Discovery of 3,3-disubstituted piperidine-derived trisubstituted ureas as highly potent soluble epoxide hydrolase inhibitors
Shen, Hong C.,Ding, Fa-Xiang,Deng, Qiaolin,Xu, Suoyu,Chen, Hsuan-shen,Tong, Xinchun,Tong, Vincent,Zhang, Xiaoping,Chen, Yuli,Zhou, Gaochao,Pai, Lee-Yuh,Alonso-Galicia, Magdalena,Zhang, Bei,Roy, Sophie,Tata, James R.,Berger, Joel P.,Colletti, Steven L.
scheme or table, p. 5314 - 5320 (2010/07/03)
3,3-Disubstituted piperidine-derived trisubstituted urea entA-2b was discovered as a highly potent and selective soluble epoxide hydrolase (sEH) inhibitor. Despite the good compound oral exposure, excellent sEH inhibition in whole blood, and remarkable se
Bredt's Rule. Part 6. The Synthesis of 5-Phenyl-1-azabicyclononan-2-one, a Bridgehead Amide
Buchanan, George L.
, p. 2669 - 2670 (2007/10/02)
6-Oxo-3-phenylpiperidine-3-propanoic acid, prepared from dimethyl 4-cyano-4-phenylheptanedioate, has been reduced selectively to the corresponding amine and then cyclised thermally or via its acid chloride to 5-phenyl-1-azabicyclononan-2-one.
