950642-64-5Relevant academic research and scientific papers
Design, synthesis, and structure-activity relationship studies of new phenolic DNA gyrase inhibitors
Luebbers, Thomas,Angehrn, Peter,Gmuender, Hans,Herzig, Silvia
, p. 4708 - 4714 (2008/02/10)
Starting from a biased needle screening hit 3a, we report herein the design and synthesis of a series of novel 2,3-dihydroisoindol-1-ones structurally related to cyclothialidine 2 with DNA gyrase inhibitory activity. In this series, some compounds exhibit
