950650-35-8Relevant academic research and scientific papers
Regiocontrolled Wacker Oxidation of Cinnamyl Azides
Carlson, Angela S.,Calcanas, Cristian,Brunner, Ryan M.,Topczewski, Joseph J.
, p. 1604 - 1607 (2018/03/23)
A highly regioselective Wacker oxidation has been developed for the oxidation of cinnamyl azides. The catalytic oxidation tolerates the azide functionality, and more than 15 β-azido ketones were isolated (25-92% yield). High regioselectivity for the aryl ketone is observed in all cases. A robustness screen was conducted to determine functional group tolerance. The products of the oxidaiton can be readily diversified.
Synthesis of enantiomerically pure γ-azidoalcohols by lipase-catalyzed transesterification
Kamal, Ahmed,Malik, M. Shaheer,Shaik, Ahmad Ali,Azeeza, Shaik
, p. 1078 - 1083 (2008/09/19)
An enantioselective synthesis of chiral γ-azidoalcohols via lipase-catalyzed resolution is described. The efficiency of various lipases and the effect of different solvents have been studied. Pseudomonas cepacia immobilized on diatomaceous earth (PS-D) in n-hexane catalyzed the transesterification process in an efficient manner providing γ-azidoalcohols in high enantiomeric excess.
