950752-52-0

Usage

Uses

Used in Pharmaceutical Industry:
(3-chloro-phenyl)-(4-chloro-pyrimidine-2-yl)-amine is used as an intermediate in the synthesis of various pharmaceuticals for its potential anti-tumor and anti-inflammatory properties. It plays a crucial role in the development of new drugs that can target and treat cancer and inflammatory conditions.
Used in Agrochemical Industry:
In the agrochemical industry, (3-chloro-phenyl)-(4-chloro-pyrimidine-2-yl)-amine is used as a potential herbicide and pesticide. Its application helps in controlling the growth of unwanted plants and pests, thereby contributing to increased crop yields and agricultural productivity.
Used in Dye Industry:
(3-chloro-phenyl)-(4-chloro-pyrimidine-2-yl)-amine is also utilized in the synthesis of various dyes due to its chemical properties. This application contributes to the production of a wide range of colored products used in different industries, such as textiles, plastics, and printing inks.

Upstream product

• 158661-60-0 2-(3-chloro-phenylamino)-pyrimidin-4-ol 
• 108-42-9 3-chloro-aniline 

Downstream Products

• 960243-31-6 tert-butyl (2S)-2-[({2-[(3-chlorophenyl)amino]pyrimidin-4-yl}amino)methyl]pyrrolidine-1-carboxylate 

Relevant academic research and scientific papers

HETEROCYCLIC ORGANIC COMPOUNDS FOR THE TREATMENT OF IN PARTICULAR MELANOMA

The present invention relates to the discovery that certain compounds inhibit, regulate and/or modulate tyrosine and serine/threonine kinase and kinase-like proteins, such as RAF kinase, a serine/threonine kinase that functions in the MAP kinase signaling

2-ANILINO-4-AMINOALKYLENEAMINOPYRIMIDINES

The present invention relates to 2-arylamino-4-(aminoalkylene)aminopyrimidines inhibitors which are inhibitors and therefore inhibit Protein Kinase C-alpha (PKC-α). The PKC-α inhibitors of the present invention are important for improving myocardial intracellular calcium cycling, resulting in improved myocardial contraction and relaxation performance and thereby slowing the progression of heart failure. The present invention further relates to compositions comprising said 2-arylamino-4-(aminoalkylene)amino-pyrimidines and to methods for controlling, abating, or otherwise slowing the progression of heart failure.

2-Anilino-4-(Heterocyclic) Amino-Pyrimidines

The present invention relates to 2-arylamino-4-(heterocyclic)aminopyrimidines inhibitors which are inhibitors and therefore inhibit Protein Kinase C-alpha (PKC-α). The PKC-α inhibitors of the present invention are important for improving myocardial intracellular calcium cycling, resulting in improved myocardial contraction and relaxation performance and thereby slowing the progression of heart failure. The present invention further relates to compositions comprising said 2-arylamino-4-(heterocyclic)amino-pyrimidines and to methods for controlling, abating, or otherwise slowing the progression of heart failure.