950758-04-0

Upstream product

• 66713-37-9 n-butyl trimethylsilylethynyl ketone 
• 950758-26-6 2-butyl-2-ethynyl-1,3-dithiolane 
• 950758-24-4 (2-butyl-1,3-dithiolan-2-ylethynyl)-trimethylsilane 
• 904928-63-8 2-butyl-2-hex-1-ynyl-1,3-dithiolane 
• 109-72-8 n-butyllithium 
• 100-52-7 benzaldehyde 

Downstream Products

• 1170731-02-8 2,4-di-butyl-3-iodo-5-phenylfuran 

Relevant academic research and scientific papers

Mercuric acetate-mediated annulation of homopropargylic alcohols having thioether substituent. A general route for the synthesis of tetrasubstituted furans from propargylic dithioacetals

Treatment of an alkyl-substituted propargylic dithioacetal with nBuLi followed by an aldehyde furnishes thio-substituted homopropargylic alcohol 7 which undergoes annulation in the presence of two equivalents of mercury acetate to give the corr

Iron-promoted elimination of β-thioalkoxy alcohols. Olefination by coupling of a carbonyl group with a dithioacetal

Treatment of propargylic dithiolanes with nBuLi followed by a carbonyl electrophile yields the corresponding propargylic dithioacetals. Upon treatment with 1 equiv of Fe(BCaC)3 and excess MeMgl, elimination of SR and OH moieties from 8 affords the corresponding olefins in satisfactory yield. Benzylic dithioacetals behave similarly. The reaction can be considered an alternative of McMurry coupling of two different carbonyl equivalents.