95081-23-5

Upstream product

• 4023-80-7 1-(4-methoxyphenyl)butan-1,3-dione 
• 1004-00-8 4-chloro-2-aminobenzenethiol 
• 89-61-2 2,5-dichloronitrobenzene 
• 95081-18-8 2-amino-4-chlorobenzenethiol sodium salt 
• 143644-62-6 p-methoxybenzoylacetone 

Relevant academic research and scientific papers

Synthesis of 6-chloro-3-methyl-4H-1,4-benzothiazines: Chlorpromazine analogs

β-Diketones or β-ketoesters (II) react with the sodium salt of 2-amino-4-chlorobenzenethiol (I) in DMSO giving 6-chloro-3-methyl-4H-1,4-benzothiazines (IIIa-h).The reaction takes place in a single-step involving condensation and oxidative cyclisation of (

Diamagnetic Susceptibilities of 4H-1,4-Benzothiazines

The experimental diamagnetic susceptibilities of a number of 4H-1,4-benzothiazines (I) have been measured.Diamagnetic susceptibilities of compounds (I) have also been estimated considering these molecules to be made of two structural units; one consisting of o-aminobenzenethiol containing the substituents and the other consisting of β-diketones/β-ketoesters.Diamagnetic susceptibily contributions of these two structural units have been calculated.The divergence between calculated and experimental values of diamagnetic susceptibilities of I is less than 1.5percent.Such an excellent agreement between calculated and experimental values is attributed to the fact that almost all the structural interactions caused by substituents have been accounted for in these calculations by considering the above two structural units.