95081-18-8

Upstream product

• 89-61-2 2,5-dichloronitrobenzene 
• 1004-00-8 4-chloro-2-aminobenzenethiol 

Downstream Products

• 1408300-14-0 (R)-5-chloro-2-(1-phenylallylthio)aniline 
• 1049160-14-6 C₁₅H₁₄ClNS 
• 1408300-17-3 (R)-2-(1-(4-bromophenyl)allylthio)-5-chloroaniline 
• 1408300-19-5 (S)-5-chloro-2-(hex-1-en-3-ylthio)aniline 
• 95081-23-5 6-chloro-2-(p-methoxybenzoyl)-3-methyl-4H-1,4-benzothiazine 
• 95081-24-6 6-chloro-3-methyl-2-(p-methylbenzoyl)-4H-1,4-benzothiazine 
• 104636-63-7 3-(2-Amino-4-chloro-phenylsulfanyl)-thiophene-2-carboxylic acid 

Relevant academic research and scientific papers

Iridium-catalyzed enantioselective allylation of sodium 2-aminobenzenethiolate: An access to chiral benzo-fused N,S-heterocycles

The use of sodium 2-aminobenzenethiolate in the enantioselective iridium catalyzed allylic substitution with a range of methyl allyl carbonates allows the concise synthesis of the branch-type products with both excellent regio- and enantioselectivities, which are functionalized N,S-containing allylic intermediates for the formation of chiral benzo-fused N,S-heterocycles.

Synthesis of 6-chloro-3-methyl-4H-1,4-benzothiazines: Chlorpromazine analogs

β-Diketones or β-ketoesters (II) react with the sodium salt of 2-amino-4-chlorobenzenethiol (I) in DMSO giving 6-chloro-3-methyl-4H-1,4-benzothiazines (IIIa-h).The reaction takes place in a single-step involving condensation and oxidative cyclisation of (