95081-59-7Relevant academic research and scientific papers
YNAZIRIDINES. METHODS OF SYNTHESIS OF A NEW TYPE OF YNAMINES
Tikhomirov, D. A.,Shubina, Yu. V.,Eremeev, A. V.
, p. 1231 - 1235 (1984)
Ways of synthesizing ynaziridines by succesive halogenation and dehydrohalogenation of enaziridino esters, the reaction of potassium aziridinide with bromophenylacetylene, the reaction of 1H-aziridines with the methyl ester of bromopropionic acid was studied.The different direction of the reaction of aziridines with bromomethylpropiolate as a function of the nature of the solvent was demonstrated.In methanol the addition of aziridine to the triple bond proceeds stereospecifically with the formation of the E-isomer.When this reaction was conducted in ether, ynaziridines were obtained for the first time.An effective method of synthesis of ynaminoesters was developed.
