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(4-Bromo-2,5-dimethoxyphenyl)boronic acid, also known as 2,5-Dimethoxy-4-bromophenylboronic acid, is an organoboronic acid compound characterized by its white to off-white crystalline solid appearance. It is a versatile reagent in organic synthesis, particularly utilized in the Suzuki coupling reaction for the formation of carbon-carbon bonds. Due to its reactivity, it is typically stored and handled under an inert atmosphere to prevent degradation. (4-Bromo-2,5-dimethoxyphenyl)boronic acid plays a significant role in the production of pharmaceuticals and agrochemicals, as well as in the development of novel materials and functional molecules within the realm of organic chemistry.

950846-26-1

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950846-26-1 Usage

Uses

Used in Organic Synthesis:
(4-Bromo-2,5-dimethoxyphenyl)boronic acid is used as a reagent in organic synthesis for the formation of carbon-carbon bonds through the Suzuki coupling reaction. This reaction is a powerful tool in constructing complex organic molecules and is widely used in the synthesis of biologically active compounds and materials.
Used in Pharmaceutical Production:
In the pharmaceutical industry, (4-Bromo-2,5-dimethoxyphenyl)boronic acid is used as a key intermediate in the synthesis of various drugs. Its ability to form carbon-carbon bonds makes it a valuable component in the development of new pharmaceuticals with improved efficacy and selectivity.
Used in Agrochemical Production:
Similarly, in the agrochemical industry, (4-Bromo-2,5-dimethoxyphenyl)boronic acid is employed as an intermediate in the synthesis of pesticides and other agrochemicals. Its use contributes to the development of more effective and environmentally friendly products for agricultural applications.
Used in the Development of Novel Materials:
(4-Bromo-2,5-dimethoxyphenyl)boronic acid is also utilized in the research and development of new materials and functional molecules. Its unique properties and reactivity make it a promising candidate for creating innovative materials with potential applications in various fields, such as electronics, energy, and medicine.

Check Digit Verification of cas no

The CAS Registry Mumber 950846-26-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,5,0,8,4 and 6 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 950846-26:
(8*9)+(7*5)+(6*0)+(5*8)+(4*4)+(3*6)+(2*2)+(1*6)=191
191 % 10 = 1
So 950846-26-1 is a valid CAS Registry Number.

950846-26-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (4-Bromo-2,5-dimethoxyphenyl)boronic acid

1.2 Other means of identification

Product number -
Other names 4-BROMO-2,5-DIMETHOXYPHENYLBORONIC ACID

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:950846-26-1 SDS

950846-26-1Downstream Products

950846-26-1Relevant articles and documents

5-HT2A AGONISTS FOR USE IN TREATMENT OF DEPRESSION

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Paragraph 0438, (2021/05/14)

The present invention relates to agonists of the 5-HT2A serotonin receptors and their medical uses. In one aspect the invention relates to 5-HT2A agonists of formula (I). In second aspect, the invention relates to selective 5-HT2A agonists of formula (II). In another aspect, the invention relates to mixed 5-HT2A/5-HT2C agonists of formula (III). In yet another aspect, the invention relates to 5-HT2A agonists for use in the treatment of a depressive disorder, more particular a 5-HT2A agonist for the use in the treatment of treatment-resistant depression.

Side functionalization of diboronic acid precursors for covalent organic frameworks

Faury, Thomas,Dumur, Frederic,Clair, Sylvain,Abel, Mathieu,Porte, Louis,Gigmes, Didier

, p. 2067 - 2075 (2013/04/23)

A series of substituted 1,4-benzenediboronic acids (BDBA) was synthesized and their thermal properties investigated. Two diboronic acids were studied as building-blocks for covalent organic framework (COF) formation, namely 2,5-dimethoxy-1,4-benzenediboronic acid and 2-nitro-1,4-benzeneboronic acid. Interestingly, substitution of the BDBA core caused a dramatic decrease of the polymerization temperature leading to the formation of a less organized structure.

Aryl trihydroxyborate salts: Thermally unstable species with unusual gelation abilities

Moy, Cheryl L.,Kaliappan, Raja,McNeil, Anne J.

, p. 8501 - 8507 (2011/12/04)

A series of aryl trihydroxyborate salts were synthesized and found to form gels in benzene. The compounds were thermally unstable and readily underwent protodeboronation in solution and the solid state. Gelation could be induced without decomposition via sonication. Subsequent characterization studies revealed an unusual dependence of gel properties on alkyl chain length.

2-AMIN0-5, 7-DIHYDR0-6H- PYRROLO [3, 4-D] PYRIMIDINE DERIVATIVES AS HSP-90 INHIBITORS FOR TREATING CANCER

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Page/Page column 118-119, (2008/12/08)

The present invention is directed to compounds of formula (I), and pharmaceutically acceptable salts thereof, their synthesis, and their use as HSP-90 inhibitors.

Synthesis of penta-p-phenylenes with oligo(ethylene glycol) side chains

López-Romero, J. Manuel,Rico, Rodrigo,Martínez-Mallorquín, Rocío,Hierrezuelo, Jesús,Guillén, Elena,Cai, Chengzhi,Otero, J. Carlos,López-Tocón, Isabel

, p. 6075 - 6079 (2008/03/12)

We report an efficient synthesis of a series of penta-p-phenylene derivatives with four side chains of various lengths, including deca(ethylene glycol) groups. The key feature of the synthesis is that the side chains are efficiently introduced in the last step, facilitating optimization of the side chains for different applications. Raman spectroscopy study indicates a similarly high rigidity for all these compounds, even those with long oligo(ethylene glycol) side chains. The deca(ethylene glycol)-substituted penta-p-phenylene derivatives are versatile building blocks for construction of nanometric, tripod-shaped adsorbates for biological applications.

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