950993-49-4

Basic information

• Product Name: 2-bis(methylthio)phenylmethylpyridine
• Synonyms: 2-bis(methylthio)phenylmethylpyridine
• CAS NO: 950993-49-4
• Molecular Weight: 261.412
• Mol File: 950993-49-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-bis(methylthio)phenylmethylpyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bis(methylthio)phenylmethylpyridine(950993-49-4)
• EPA Substance Registry System: 2-bis(methylthio)phenylmethylpyridine(950993-49-4)

Safety Data

• Hazardous Substances Data: 950993-49-4(Hazardous Substances Data)

Upstream product

• 101-82-6 2-Benzylpyridine 
• 624-92-0 Dimethyldisulphide 

Downstream Products

• 91-02-1 phenyl(pyridin-2-yl)methanone 

Relevant articles and documents

The methyl group as a source of structural diversity in heterocyclic chemistry: Side chain functionalization of picolines and related heterocycles

(Chemical Equation Presented) The reaction of 2-picoline at the methyl group with NDA and KDA followed by dimethyldisulfide trapping furnished, respectively, dithioacetals and trithioortho esters with high selectivity. The method was successfully applied to other methyl-substituted pyridines, quinolines, and pyrazines. Dithioketals were prepared by a one-pot procedure involving the reaction of metalated 2-picoline with 2 equiv of dimethyldisulfide followed by in situ trapping with a second electrophile. All of the generated thio-substituted compounds were efficiently transformed in presence of mercury salts or under oxidizing conditions to other functional groups comprising aldehydes, ketones, ketals, thiol esters, orthoesters, and esters.