951000-48-9Relevant academic research and scientific papers
In-Depth Assessment of the Palladium-Catalyzed Fluorination of Five-Membered Heteroaryl Bromides
Milner, Phillip J.,Yang, Yang,Buchwald, Stephen L.
, p. 4775 - 4780 (2015/10/28)
A thorough investigation of the challenging Pd-catalyzed fluorination of five-membered heteroaryl bromides is presented. Crystallographic studies and density functional theory (DFT) calculations suggest that the challenging step of this transformation is
Nuclear fluorination of 2,4-diarylthiazoles with Accufluor
Campbell, Timmeda F.,Stephens, Chad E.
, p. 1591 - 1594 (2008/09/18)
A series of 2,4-diphenylthiazole derivatives were synthesized and directly fluorinated at the 5-position by reaction with the N-F fluorinating reagent Accufluor. Although fluorination occurred selectively at the thiazole ring, it was always inc
