95105-01-4

Upstream product

• 94955-39-2 6-(4-aminophenyl)-5-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one 
• 42783-36-8 (d)-5-phenyl-1,3-dioxolan-2,4-dione 

Relevant academic research and scientific papers

Triazine derivatives, and pharmaceutical compositions comprising the same

New triazine derivatives represented by the formula: STR1 wherein R1 is hydrogen; halogen or hydrazinocarbonyl(lower)alkyl; R2 is hydrazino; azido; halosulfonyl; mono- or di(lower)alkylamino; mono- or di-(lower alkynylamino; pyridylamino; lower alkylideneamino substituted by furyl pyridyl or aryl; mono- or di-(lower)alkylamino substituted by amino, carboxy, hydroxy, ureido, lower alkoxy, lower alkoxycarbonyl, lower alkoxy(lower)alkoxy, aryl, furyl, pyridyl, phthalimido, or succinimido; N-methyl(lower)alkanoylamino; N-containing, 5- or 6-membered heterocyclic group optionally substituted by oxo, lower alkyl and/or lower alkoxycalbonyl; lower alkoxy substituted by hydroxy and lower alkylamino; or a group of the formula STR2 in which R3 is hydrogen; lower alkyl or ar(lower)alkyl; R4 is pyridyl; aryl; styryl; alkynyl; lower alkoxycarbonyl; α-hydroxybenzyl; lower alkanoyl; carboxy; or lower alkyl substituted by halogen, amino, hydroxy, carboxy, lower alkanoyl, lower alkanoyloxy, lower alkoxycarbonyl, morpholino, lower alkoxycarbonylamino, 1-methyl-2-oxo-1,2,3,4-tetrahydroquinolyloxy, mono- or di(lower)alkylamino, piperazinyl being substituted with hydroxy(lower)alkyl or furoyl, or pyrrolidino; and pharmaceutically acceptable salt thereof, which are useful in the treatment of hypertension, thrombosis and ulcer in human beings and animals.