95115-20-1Relevant academic research and scientific papers
Incorporation of carbohydrates and peptides into large triazine-based screening libraries using automated parallel synthesis
Gustafson, Gary R.,Baldino, Carmen M.,O'Donnell, Mary-Margaret E.,Sheldon, Adrian,Tarsa, Robert J.,Verni, Christopher J.,Coffen, David L.
, p. 4051 - 4065 (1998)
A procedure for the sequential, selective derivatization of cyanuric chloride that allows for the incorporation of carbohydrates and peptides has been elucidated. As a result, large combinatorial arrays of individual derivatives, over 40,000 in all, have
MECHANISM OF THE REACTION OF GLYCIDYL ESTERS WITH CARBOXYLIC ACIDS
Klebanov, M. S.,Kir'yazev, F. Yu.,Chervinskii, A. Yu.,Shologon, I. M.
, p. 2193 - 2196 (2007/10/02)
The kinetics of the reactions of 1-phenoxy-2,3-epoxypropane and 2,3-epoxypropylbenzoate with carboxylic acids were investigated.A new reaction mechanism is proposed to explain the anomalously high reactivity of the glycidyl esters.The mechanism involves protonation of the oxygen of the carbonyl group in the ester followed by intramolecular electrophilic attack on the oxirane oxygen by the carbonyl carbon atom, accompanied by opening of the epoxide ring and transfer of the acyl fragment in the glycidyl ester molecule.
