951238-20-3Relevant academic research and scientific papers
Selective detection of the reduced form of glutathione (GSH) over the oxidized (GSSG) form using a combination of glutathione reductase and a Tb(III)-cyclen maleimide based lanthanide luminescent 'Switch On' assay
McMahon, Brian K.,Gunnlaugsson, Thorfinnur
, p. 10725 - 10728 (2012/08/27)
The synthesis of a novel Tb(III) luminescent probe for the detection of thiols is presented. The probe 1.Tb, possessing a maleimide moiety, as its sulfhydryl acceptor, was poorly emitting in aqueous pH 7 solution in the absence of a thiol. However, upon addition of thiols such as glutathione (GSH), large enhancements were observed, particularly within the physiological pH range. In contrast no enhancements were observed in the presence of the oxidized form of glutathione (GSSG), except in the presence of the enzyme glutathione reductase and NADPH which enabled 1.Tb to be used to observe the enzymatic reduction of GSSG to GSH in real time.
The recognition of anions using delayed lanthanide luminescence: The use of Tb(iii) based urea functionalised cyclen complexes
Dos Santos, Cidalia Maria Gomes,Gunnlaugsson, Thorfinnur
experimental part, p. 4712 - 4721 (2009/10/30)
A cyclen based lanthanide luminescent sensor, Tb.1, has been developed by taking advantage of a combination of hydrogen bonding and f-metal ion coordination binding sites for anionic species. Analysis of the ground state, the emission from the singlet and
Lanthanide luminescent anion sensing: Evidence of multiple anion recognition through hydrogen bonding and metal ion coordination
Dos Santos, Cidalia M. G.,Fernandez, Pablo Barrio,Plush, Sally E.,Leonard, Joseph P.,Gunnlaugsson, Thorfinnur
, p. 3389 - 3391 (2008/02/13)
The delayed lanthanide luminescence of the terbium [Tb(iii)] diaryl-urea complex 1·Tb is significantly enhanced upon sensing of dihydrogenphosphate (H2PO4-) in CH 3CN, which occurs through multiple anion binding
