951325-91-0

Basic information

• Product Name: (2S,4R,6R,E)-2-phenyl-6-styryltetrahydro-2H-pyran-4-ol
• Synonyms: (2S,4R,6R,E)-2-phenyl-6-styryltetrahydro-2H-pyran-4-ol
• CAS NO: 951325-91-0
• Molecular Weight: 280.367
• Mol File: 951325-91-0.mol

Chemical Properties

• CAS DataBase Reference: (2S,4R,6R,E)-2-phenyl-6-styryltetrahydro-2H-pyran-4-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4R,6R,E)-2-phenyl-6-styryltetrahydro-2H-pyran-4-ol(951325-91-0)
• EPA Substance Registry System: (2S,4R,6R,E)-2-phenyl-6-styryltetrahydro-2H-pyran-4-ol(951325-91-0)

Safety Data

• Hazardous Substances Data: 951325-91-0(Hazardous Substances Data)

Upstream product

• 951325-93-2 (4R,6S)-6-(tert-butyldimethylsilyl)oxy-4-hydroxy-6-phenyl-1-hexene 
• 951325-89-6 (5R,7S)-7-(tert-butyldimethylsilyl)oxy-1,5-dihydroxy-1,7-diphenyl-2-heptene 
• 951325-88-5 (5R,7S)-7-(tert-butyldimethylsilyl)oxy-5-hydroxy-1,7-diphenyl-2-hepten-1-one 
• 412912-89-1 (S)-3-((tert-butyldimethylsilyl)oxy)-3-phenylpropanal 
• 956035-49-7 (2S,4R,6R)-2-phenyl-6-[(E)-styryl]tetrahydro-2H-pyran-4-yl acetate 
• 951325-90-9 C₁₉H₂₂O₃ 

Downstream Products

• 951325-77-2 5-epi-diospongin A 
• 956035-52-2 (2S,4S,6R)-2-phenyl-6-[(E)-styryl]tetrahydro-2H-pyran-4-yl-4-nitrobenzoate 
• 956035-54-4 (2R,4S,6S)-2-(2-oxo-2-phenylethyl)-6-phenyltetrahydro-2H-pyran-4-yl-4-nitrobenzoate 

Relevant articles and documents

Stereoselective synthesis of (-)-diospongins A and B and their stereoisomers at C-5

Antiosteoporotic diarylheptanoids (-)-diospongins A (1) and B (2) were synthesized stereoselectively. The key steps in the synthesis include a stereospecific PdII-catalyzed cyclization of chiral 1,5,7-trihydroxy-2-heptenes, 6a and 6b, to form c

Total synthesis of diospongin A via an enzymatic kinetic resolution of (±)-tetrahydropyranol derived from prins cyclization

A concise and efficient total synthesis of diospongin A is described; it utilizes Prins cyclization and enzymatic kinetic resolution as key steps. This is the first report on the synthesis of diospongin A by means of lipase-mediated transesterification of