951645-47-9Relevant academic research and scientific papers
Synthesis and characterization of some new pyrazolines and their inhibitory potencies against carbonic anhydrases
?elik, Gonca,?entürk, Murat,Arslan, Tayfun,Ekinci, Deniz
, (2020)
The inhibition of the two human cytosolic carbonic anhydrase (hCA; EC 4.2.1.1) isozymes I and II with some new pyrazoline derivatives was investigated for the first time. The structures of the newly synthesized pyrazoline derivatives were characterized by
Chiral Phosphoric Acid Catalyzed Asymmetric Synthesis of 2-Substituted 2,3-Dihydro-4-quinolones by a Protecting-Group-Free Approach
Saito, Kodai,Moriya, Yuka,Akiyama, Takahiko
supporting information, p. 3202 - 3205 (2015/07/15)
Chiral 2-substituted 2,3-dihydro-4-quinolones were synthesized based on the chiral phosphoric acid catalyzed intramolecular aza-Michael addition reaction using N-unprotected 2-aminophenyl vinyl ketones as substrates in good yields with high enantioselectivities. (Chemical Equation Presented).
Synthesis and protein tyrosine phosphatase 1B-Inhibitory activity of chalcones
Zhao, Fei,Zhao, Qing-Jie,Zhang, Da-Zhi,Jin, Yong-Sheng,Zhang, Wei
experimental part, p. 5339 - 5342 (2012/06/30)
Protein tyrosine phosphatase 1B (PTP1B) is an effective target for the treatment of type 2 diabetes and obesity. So far less work has been conducted in the structure-activity relationship of the PTP1B inhibitory activity of chalcones. In this work, a libr
