951666-96-9

Upstream product

• 51282-49-6 methyl 5-chloro-2-nitrobenzoate 
• 1849-36-1 para-nitrobenzenethiol 
• 951666-94-7 methyl 2-mercapto-6-nitrobenzoate 
• 350-46-9 4-Fluoronitrobenzene 
• 2516-95-2 5-chloro-2-nitrobenzoic acid 

Downstream Products

• 951666-98-1 2-Amino-5-(4-amino-phenylsulfanyl)-benzoic acid methyl ester 

Relevant academic research and scientific papers

HOMOGENEOUS TIME RESOLVED FLUORESCENCE BASED TEST SYSTEM

The present invention concerns a fluorescence resonance energy transfer based high throughput test system to measure the formation of the HIV gp41 six-helix bundle. In a first embodiment the current invention relates to a homogeneous time resolved fluorescence-based test system comprising a first helical polypeptide consisting essentially of the sequence of IQN36 (SEQ ID NO:1); a second helical polypeptide consisting essentially of the sequence of C34 (SEQ ID NO: 2) wherein said IQN36 is labeled with a light emitting fluorophore and said C34 is labeled with an ultra-violet excitable fluorophore.

BIS-ARYL COMPOUNDS FOR USE AS MEDICAMENTS

There is provided compounds of formula I, wherein ring A, D1, D2a, D2b, D3, L1, Y1, L3 and Y3 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of leukotriene C4 synthase is desired and/or required, and particularly in the treatment of a respiratory disorder and/or inflammation.