951670-96-5

Upstream product

• 1191-95-3 cyclobutanone 
• 108-95-2 phenol 

Downstream Products

• 1358755-49-3 4-[1-(4-hydroxyphenyl)cyclobutyl]phenyl trifluoromethanesulfonate 
• 1141359-77-4 4-{1-[4-(pyridin-2-ylmethoxy)phenyl]cyclobutyl}phenol 
• 951670-98-7 methyl 4-[1-(4-hydroxyphenyl)cyclobutyl]benzoate 

Relevant academic research and scientific papers

3,3-Diphenylpentane skeleton as a steroid skeleton substitute: Novel inhibitors of human 5α-reductase 1

We designed and synthesized novel type 1 5α-reductase inhibitors by using 3,3-diphenylpentane skeleton as a substitute for the usual steroid skeleton. 4-(3-(4-(N-Methylacetamido)phenyl)pentan-3-yl)phenyl dibenzylcarbamate (11k) is a competitive 5α-reductase inhibitor with the IC50 value of 0.84 μM.

DIPHENYL SUBSTITUTED CYCLOALKANES

The present invention provides compounds of Formula I which are FLAP inhibitors useful as anti-atherosclerotic, anti-asthmatic, anti-allergic, anti-inflammatory and cytoprotective agents.

GLUCAGON RECEPTOR ANTAGONIST COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE

Glucagon receptor antagonist compounds are disclosed. The compounds are useful for treating type 2 diabetes and related conditions. Pharmaceutical compositions and methods of treatment are also included.