951682-11-4

Basic information

• Product Name: 3'-methylacetophenone oxime acetate
• Synonyms: 3'-methylacetophenone oxime acetate
• CAS NO: 951682-11-4
• Molecular Weight: 191.23
• Mol File: 951682-11-4.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 3'-methylacetophenone oxime acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-methylacetophenone oxime acetate(951682-11-4)
• EPA Substance Registry System: 3'-methylacetophenone oxime acetate(951682-11-4)

Safety Data

• Hazardous Substances Data: 951682-11-4(Hazardous Substances Data)

Upstream product

• 585-74-0 3-Methylacetophenone 
• 23040-54-2 1-m-tolyl-ethanone oxime 
• 108-24-7 acetic anhydride 

Downstream Products

• 1206606-79-2 C₁₁H₁₂INO₂ 
• 1462327-95-2 dimethyl 5-(m-tolyl)-1H-pyrrole-2,3-dicarboxylate 
• 1370640-77-9 2-(toluene-4-sulfonyl)-1-m-tolylethanone 
• 895138-61-1 1-phenyl-3-(m-tolyl)-1H-pyrazole 
• 1295522-07-4 1,7-dimethyl-3,4-diphenyl-isoquinoline 

Relevant articles and documents

Copper(0)/PPh3-Mediated Bisheteroannulations of o-Nitroalkynes with Methylketoximes Accessing Pyrazo-Fused Pseudoindoxyls

A copper(0)/PPh3-mediated cascade bisheteroannulation reaction of o-nitroalkynes with methylketoximes has been developed that provides viable access to a diverse range of pyrazo-fused pseudoindoxyl compounds. Synthetically useful functional groups including sensitive C-I bonds are compatible with this system. Mechanistic studies suggest a reaction cascade involving sequential PPh3-mediated deoxygenative cycloisomerization and copper-catalyzed [3 + 2] pyrazo-annulation.

Copper-catalyzed synthesis of thiazol-2-yl ethers from oxime acetates and xanthates under redox-neutral conditions

A novel copper-catalyzed annulation of oxime acetates and xanthates for the synthesis of thiazol-2-yl ethers with remarkable regioselectivity has been developed. Various oxime acetates, whether derived from aryl ketones or alkyl ketones, or natural product cores are suitable for this conversion. Unique dihydrothiazoles were also obtained when both reaction sites were methine. Mechanistic studies indicated that imino copper(iii) intermediates were involved. In addition, this protocol proceeded under redox-neutral conditions and did not require additives or ligands.

Iron-Catalyzed Synthesis of 2H-Imidazoles from Oxime Acetates and Vinyl Azides under Redox-Neutral Conditions

A novel and versatile method for the synthesis of 2H-imidazoles via iron-catalyzed [3 + 2] annulation from readily available oxime acetates with vinyl azides has been developed. This denitrogenative process involved N-O/N-N bond cleavages and two C-N bond formations to furnish 2,4-substituted 2H-imidazoles. This protocol was performed under mild reaction conditions and needed no additives or ligands. Furthermore, this is a green reaction involving oxime acetate as internal oxidant, acetic acid, and nitrogen as byproducts.