95176-98-0Relevant academic research and scientific papers
Peptide backbone-to-backbone cyclisation as an avenue to β-turn mimics
Hermkens,Dinther,Joukema,Wagenaars,Ottenheijn
, p. 9271 - 9274 (2007/10/02)
1,3-Dipolar cycloaddition of the nitrone functionality of 13 and the alkene functionality of 8 yields the backbone-to-backbone cyclised peptides 14-16. The conformation of these structures is such that they are p-turn mimics. They differ in their C3/C5 stereochemistry with discrete conformational differences.
