951770-22-2

Basic information

• Product Name: 10-HydroxycaMptothecin acetate
• Synonyms: (4S)-4-(Acetyloxy)-4-ethyl-9-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
• CAS NO: 951770-22-2
• Molecular Formula: C22H18N2O6
• Molecular Weight: 406.38812
• Mol File: 951770-22-2.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Density: 1.53±0.1 g/cm3 (20 ºC 760 Torr)
• CAS DataBase Reference: 10-HydroxycaMptothecin acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 10-HydroxycaMptothecin acetate(951770-22-2)
• EPA Substance Registry System: 10-HydroxycaMptothecin acetate(951770-22-2)

Safety Data

• Hazardous Substances Data: 951770-22-2(Hazardous Substances Data)

Usage

Uses

10-?Hydroxycamptothecin Acetate is a derivative of Camptothecin (C175150), an antitumor compound used in the treatment of hyperproliferative diseases.

Upstream product

• 19685-09-7 (S)-10-hydroxycamptothecin 
• 108-24-7 acetic anhydride 

Relevant articles and documents

A camptothecin phospholipid compound, its pharmaceutical composition and application

The invention discloses a camptothecin phospholipid compound, a preparation method, a drug composition and application thereof. The drug composition is a camptothecin phospholipid compound or a medical composition combining the camptothecin phospholipid compound with a carrier that is acceptable in pharmacodynamics, can be taken as a liquid preparation, solid preparation, semisolid preparation, capsules, granules, gel or injection; the drug composition is the camptothecin phospholipid compound or lipidosome nano-particles prepared from the camptothecin phospholipid compound and an assistant, the grain size of the drug composition is 10-1000 nanometers; the camptothecin phospholipid compound or the camptothecin phospholipid compound lipidosome can quickly release active camptothecin phospholipid compound crude drugs, thereby having a strong anti-tumor effect; the camptothecin phospholipid compound and lipidosome nano particles of the compound can be used as a liquid preparation, solid preparation, semisolid preparation, sterilization preparation and sterile preparation, are low in toxicity, and can be used for efficiently treating various tumors.