951770-22-2 Usage
Uses
Used in Pharmaceutical Industry:
10-Hydroxycamptothecin acetate is used as an antitumor agent for the treatment of hyperproliferative diseases, particularly solid tumors. Its mechanism of action involves the inhibition of topoisomerase I, which leads to the prevention of DNA replication and transcription, ultimately resulting in the death of cancer cells.
Used in Cancer Therapy:
10-Hydroxycamptothecin acetate is used as a chemotherapeutic agent for the treatment of various types of cancer, including ovarian, cervical, and lung cancer. Its ability to target and inhibit topoisomerase I makes it a promising candidate for the development of novel cancer therapies.
Used in Drug Development:
10-Hydroxycamptothecin acetate serves as a key compound in the development of new drugs and drug delivery systems. Researchers are exploring its potential to be combined with other chemotherapeutic agents or encapsulated in nanoparticles to improve its efficacy, bioavailability, and targeted delivery to cancer cells.
Check Digit Verification of cas no
The CAS Registry Mumber 951770-22-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,5,1,7,7 and 0 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 951770-22:
(8*9)+(7*5)+(6*1)+(5*7)+(4*7)+(3*0)+(2*2)+(1*2)=182
182 % 10 = 2
So 951770-22-2 is a valid CAS Registry Number.
951770-22-2Relevant academic research and scientific papers
A camptothecin phospholipid compound, its pharmaceutical composition and application
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Paragraph 0119, (2017/10/06)
The invention discloses a camptothecin phospholipid compound, a preparation method, a drug composition and application thereof. The drug composition is a camptothecin phospholipid compound or a medical composition combining the camptothecin phospholipid compound with a carrier that is acceptable in pharmacodynamics, can be taken as a liquid preparation, solid preparation, semisolid preparation, capsules, granules, gel or injection; the drug composition is the camptothecin phospholipid compound or lipidosome nano-particles prepared from the camptothecin phospholipid compound and an assistant, the grain size of the drug composition is 10-1000 nanometers; the camptothecin phospholipid compound or the camptothecin phospholipid compound lipidosome can quickly release active camptothecin phospholipid compound crude drugs, thereby having a strong anti-tumor effect; the camptothecin phospholipid compound and lipidosome nano particles of the compound can be used as a liquid preparation, solid preparation, semisolid preparation, sterilization preparation and sterile preparation, are low in toxicity, and can be used for efficiently treating various tumors.
