951777-98-3Relevant academic research and scientific papers
2-METHYLENE-20(21)-DEHYDRO-19,24,25,26,27,-PENTANOR-VITAMIN D ANALOGS
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Paragraph 0031, (2013/03/26)
This invention discloses 2-methylene-20(21)-dehydro-19,24,25,26, 27-pentanor-vitamin D analogs, and specifically 2-methylene-20(21)-dehydro-19,24,25,26,27-pentanor-1α-hydroxyvitamin D3, and pharmaceutical uses therefor. This compound exhibits r
2-METHYLENE-19,23,24-TRINOR-1ALPHA-HYDROXYVITAMIN D3
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Paragraph 0050; 0051; 0052, (2013/03/26)
Compounds of Formula I are provided where R1 and R2 are independently selected from H or hydroxy protecting groups. Such compounds may be used in preparing pharmaceutical compositions and are useful in treating a variety of biologica
Synthesis and biological activity of 2-(3′-hydroxypropylidene)- 1α-hydroxy-19-norvitamin D analogues with shortened alkyl side chains
Glebocka, Agnieszka,Sicinski, Rafal R.,Plum, Lori A.,Deluca, Hector F.
experimental part, p. 6832 - 6842 (2011/12/04)
As a continuation of our efforts directed to vitamin D compounds of promising biological properties, 19-norvitamins 9-13, possessing a 3′-hydroxypropylidene fragment attached to C-2 and shortened 17β-alkyl chains, were synthesized. A new synthetic pathway
2-Methylene-20-Methyl-19,24,25,26,27-Pentanor-Vitamin D Analogs
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Page/Page column 4; 6, (2009/07/17)
This invention discloses 2-methylene-20-methyl-19,24,25,26,27-pentanor-vitamin D analogs, and specifically 2-methylene-20-methyl-1α-hydroxy-19,24,25,26,27-pentanor-vitamin D3, and pharmaceutical uses therefore. This compound exhibits activity i
1a-Hydroxy-2-(3'-Hydroxypropylidene)-19-nor-vitamin D compounds and methods of making and treatment thereof
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Page/Page column 9; 13, (2008/06/13)
Disclosed are 1α-hydroxy-2-(3′-hydroxypropylidene)-19-nor-vitamin D compounds, pharmaceutical compositions, and methods of making and treatment thereof. The compounds are generally directed to biologically active 2-alkylidene-19-nor-vitamin D compounds an
