95188-25-3Relevant academic research and scientific papers
Enantioselective hydrosilylation of prochiral ketones catalyzed by chiral BINAP-copper(I) complexes
Issenhuth, Jean-Thomas,Dagorne, Samuel,Bellemin-Laponnaz, Stéphane
, p. 353 - 357 (2010)
The CuCl/NaOt-Bu/BINAP system was found to efficiently catalyze the hydrosilylation of aryl alkyl ketones with excellent enantioselectivities by using phenyl methyl silane as a stoichiometric hydride source. High enantiomeric excesses (up to 97%) and excellent yields (up to 99%) were obtained.
Highly enantioselective hydrosilylation of simple ketones catalyzed by rhodium complexes of P-chiral diphosphine ligands bearing tert-butylmethylphosphino groups
Imamoto, Tsuneo,Itoh, Takuma,Yamanoi, Yoshinori,Narui, Rintaro,Yoshida, Kazuhiro
, p. 560 - 565 (2007/10/03)
P-Chiral diphosphine ligands, (S,S)-1,2-bis(tert-butylmethylphosphino)ethane [(S,S)-t-Bu-BisP*], (R,R)-bis(tert-butylmethylphosphino)methane [(R,R)-t-Bu-MiniPHOS], and (R,R)-2,3-bis(tert-butylmethylphosphino)quinoxaline [(R,R)-QuinoxP*], were applied to the rhodium-catalyzed enantioselective hydrosilylation of simple ketones. The corresponding secondary alcohols were obtained in high yields with good to excellent enantiomeric excesses of up to 99%.
ENANTIOSELECTIVE HYDROSILYLATION OF ACETOPHENONE WITH RHODIUM /OXAZOLINES CATALYSTS
Balavoine, G.,Clinet, J.C.,Lellouche, I.
, p. 5141 - 5144 (2007/10/02)
N-chelate ligands based on chiral oxazolines are efficient co-catalysts in the enantioselective hydrosilylation of acetophenone with α-naphtylphenylsilane.Enantiomeric excess as up to 80percent have been achieved.
Asymmetric Catalyses, 14. Enantioselective Hydrosilylation of Prochiral Ketones with Rh- and Pt-Complexes of Optically Active N-Chelate Ligands
Brunner, Henri,Reiter, Barbara,Riepl, Georg
, p. 1330 - 1354 (2007/10/02)
N-chelate ligands with a lateral chiral center, which derive from optically active primary amines, amino acids, and amino acid derivatives, catalyze in Rh and Pt complexes the enantioselective hydrosilylation of acetophenone, benzyl methyl ketone, and tert-butyl methyl ketone with diphenyl- and 1-naphthylphenylsilane.The ketones are transformed into the corresponding silyl ethers which on hydrolysis yield the alcohols 1-phenylethanol, 1-phenyl-2-propanol and 3,3-dimethyl-2-butanol. 37 N ligands 1 - 37 with 2 (I) and K (XX) as well as 21 isolated complexes II - XIX and XXI - XXIII are tested.The best optical inductions exceed considerably those which were obtained with optically active phosphane containing catalysts used up to now.
