952023-32-4Relevant academic research and scientific papers
Synthesis and biological evaluation of bicyclo[3.3.0] octane derivatives as dipeptidyl peptidase 4 inhibitors for the treatment of type 2 diabetes
Cho, Tang Peng,Gang, Lin Zhi,Long, Yang Fang,Yang, Wang,Qian, Wang,Lei, Zhang,Jing, Luo Jing,Ying, Feng,Ke, Yan Pang,Ying, Leng,Jun, Feng
scheme or table, p. 3521 - 3525 (2010/08/20)
A series of novel bicyclo[3.3.0]octane derivatives have been synthesized and found to be dipeptidyl peptidase 4 (DPP-4) inhibitors. Compounds 10a and 10b demonstrate good efficacies in oral glucose tolerance tests.
Dicyclooctane Derivatives, Preparation Processes and Medical Uses Thereof
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Page/Page column 33, (2009/07/18)
The present invention relates to new dicyclooctane derivates represented by general formula (I), preparation processes and pharmaceutical compositions containing them, and to uses for treatment especially for dipeptidyl peptidase inhibitor (DPPIV), in which each substituent group of general formula (I) is as defined in specification.
DICYCLOOCTANE DERIVATES, PREPARATION PROCESSES AND MEDICAL USES THEREOF
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Page/Page column 42, (2009/01/24)
The present invention relates to new dicyclooctane derivates represented by general formula (I), preparation processes and pharmaceutical compositions containing them, and to uses for treatment especially for dipeptidyl peptidase inhibitor (DPPIV), in which each substituent group of general formula (I) is as defined in specification
