952023-91-5

Upstream product

• 15617-18-2 bis(benzonitrile)palladium(II) dichloride 
• 1107608-80-9 2,3-bis[(S)-(1,1-dimethylethyl)methylphosphino]quinoxaline 
• 1107608-80-9 (R,R)-(-)-2,3-bis(tert-butylmethylphosphino)qinoxaline 

Relevant academic research and scientific papers

Congested C-C bonds by Pd-catalyzed enantioselective allyl-allyl cross-coupling, a mechanism-guided solution

Under the influence of a chiral bidentate diphosphine ligand, the Pd-catalyzed asymmetric cross-coupling of allylboron reagents and allylic electrophiles establishes 1,5-dienes with adjacent stereocenters in high regio-and stereoselectivity. A mechanistic study of the coupling utilizing reaction calorimetry and density functional theory analysis suggests that the reaction operates through an inner-sphere 3,3′-reductive elimination pathway, which is both rate-defining and stereodefining. Coupled with optimized reaction conditions, this mechanistic detail is used to expand the scope of allyl-allyl couplings to allow the generation of 1,5-dienes with tertiary centers adjacent to quaternary centers as well as a unique set of cyclic structures.

Structures and redox properties of metal complexes of the electron-deficient diphosphine chelate ligand R,R-QuinoxP

The air-stable chiral diphosphine chelate ligand R,R-QuinoxP (L; 2,3-bis(terf-butylmethylphosphino)-quinoxaline) as developed by Imamoto et al. has been used to obtain the crystallographically characterized complexes (L)PtCl2 (1), (L)PdCl2