952024-09-8Relevant articles and documents
Cobalt carbonyl-catalyzed carbonylation of functionalized aziridines to versatile β-lactam building blocks
Piens, Nicola,Van Hecke, Kristof,Vogt, Dieter,D'Hooghe, Matthias
, p. 4816 - 4821 (2017/07/10)
The Co2(CO)8-catalyzed carbonylation of different classes of non-activated aziridines with diverse substitution patterns was investigated. Special attention was devoted to selectivity issues and reaction optimization. This study resu
Synthesis of 1-arylmethyl-2-(2-cyanoethyl)aziridines and their rearrangement into novel 2-(aminomethyl)cyclopropanecarbonitriles
D'Hooghe, Matthias,Vervisch, Karel,De Kimpe, Norbert
, p. 7329 - 7332 (2008/02/11)
(Chemical Equation Presented) 1-Arylmethyl-2-(bromomethyl)aziridines were transformed into novel 2-(2-cyanoethyl)aziridines upon treatment with α-lithiated trimethylsilylacetonitrile in THF in an efficient and straightforward approach. The latter aziridin