160676-81-3Relevant academic research and scientific papers
Synthesis and biological evaluation of novel quinoline-piperidine scaffolds as antiplasmodium agents
Boone, Maya,Chibale, Kelly,Combrinck, Jill,D'hooghe, Matthias,Mangelinckx, Sven,Smith, Peter J.,Van Puyvelde, Julie,Van de Walle, Tim
, (2020/05/13)
The parasitic disease malaria places almost half of the world's population at risk of infection and is responsible for more than 400,000 deaths each year. The first-line treatment, artemisinin combination therapies (ACT) regimen, is under threat due to em
A novel entry toward 2-imino-1,3-thiazolidines and 2-imino-1,3-thiazolines by ring transformation of 2-(thiocyanomethyl)aziridines
D'hooghe, Matthias,Waterinckx, Alex,De Kimpe, Norbert
, p. 227 - 232 (2007/10/03)
(Chemical Equation Presented). A new, efficient, and straightforward synthesis of 3-arylmethyl-4-chloromethyl-2-imino-1,3-thiazolidines and 2-(N-acylimino)-3-arylmethyl-4-chloromethyl-1,3-thiazolidines has been developed by ring transformation of 1-arylme
Electron transfer induced ring opening of 2-(bromomethyl)aziridines by magnesium in methanol
Tehrani, Kourosch Abbaspour,NguyenVan, Tuyen,Karikomi, Michinori,Rottiers, Mario,De Kimpe, Norbert
, p. 7145 - 7152 (2007/10/03)
Magnesium metal in methanol was used as a simple electron transfer induced ring-opening reagent of 2-(bromomethyl)aziridines to afford allylamines derivatives in 70-90% yield.
